My research interests are focused on image guidance in neurosurgery, including open and minimally invasive procedures. I have been working on methods and algorithms to improve the accuracy of image guidance and image updating for intraoperative brain deformation and spine motion compensation at multiple stages. We have designed and implemented intraoperative image acquisition systems for calibration, data collection and processing, such as intraoperative stereovision and 3D ultrasound. I have been working in the operating room (OR) as well as the Center for Surgical Innovation (CSI) at DHMC on data collection, intraoperative CT and MR imaging, real time computation, and intraoperative feedback to improve the accuracy of image guidance in 400+ OR cases. I am familiar with image-guided systems, intraoperative imaging techniques and instruments, and the clinical environment in general, and have expertise in image processing, image registration, computational modeling, and optimization. I have also worked closely with Medtronic in an effort to provide model updated images to the Medtronic StealthStation navigation system.