Xianhuo Wang

My research topics: 1. Immune checkpoints and immunotherapy in tumors: Focus on the PD-1/PD-L1, CD73/A2aR, TIM3, CD58, OX40 and other novel immune checkpoints. 2. Tumor microenvironment and molecular classifications: Focus on the study of disorders of immune microenvironment caused by genetic and epigenetic modifications (including m6A), and immune-related classifications (including transcriptional and mutational signatures) in lymphoma. 3. Focus on illustrating the resistance genes and mechanisms of novel targeted drugs (including XPO1 inhibitor, p53 inhibitor, PIM1 inhibitor), and dynamic detection (including ctDNA) in lymphoma.