基本信息
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Bio
Dr. Web Cavenee has fundamentally changed the way scientists now think about the onset of cancer and its progression. He provided the first indisputable evidence of the existence of tumor suppressor genes.
Dr. Cavenee’s original research sought to define the genetic lesions in retinoblastoma and led to evidence that there’s tumor suppression in humans. Today, mutations of tumor suppressor genes have been identified in more than half of all tumors, including those of muscle, melanocytes, kidney, prostate and breast. Gene therapies are being tested that would reverse gene mutations (or their effects) in cancer cells. These therapies hold tremendous promise for patients with brain tumors and many other cancers.
Dr. Cavenee’s original research sought to define the genetic lesions in retinoblastoma and led to evidence that there’s tumor suppression in humans. Today, mutations of tumor suppressor genes have been identified in more than half of all tumors, including those of muscle, melanocytes, kidney, prostate and breast. Gene therapies are being tested that would reverse gene mutations (or their effects) in cancer cells. These therapies hold tremendous promise for patients with brain tumors and many other cancers.
Research Interests
Papers共 649 篇Author StatisticsCo-AuthorSimilar Experts
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Journal of cellular physiology (2024)
Mio Harachi,Kenta Masui, Erika Shimizu, Kumiko Murakami,Hiromi Onizuka,Yoshihiro Muragaki,Takakazu Kawamata,Hisako Nakayama,Mariko Miyata,Takashi Komori,Webster K. Cavenee,Paul S. Mischel,
Acta Neuropathologica Communicationsno. 1 (2024): 1-17
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Author Statistics
#Papers: 652
#Citation: 123855
H-Index: 132
G-Index: 351
Sociability: 8
Diversity: 1
Activity: 2
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