基本信息
浏览量:1
职业迁徙
个人简介
My research complements my clinical practice: age-related macular degeneration (AMD) (the commonest cause of blindness in the western world). It focuses on the pathogenesis and treatments of AMD and other chronic eye diseases (clinical and laboratory). Current treatments are suboptimal. As the population ages the prevalence of AMD will increase. My research aims to improve disease outcome. There are no suitable animal or inv vitro models for AMD. My laboratory is the first to have cultured, in vitro, human inner choroidal endothelial cells (the site of the disease) for experiments into the disease. We are currently in the process of determining genomic differences between these cells and other endothelial cells in the eye and from other locations (eg HUVEC) in order to determine molecular targeting. Some of our work has been in collaboration with a laboratory in Kings' College, London who have expertise in microarrays and supporting validating technologies. AMD seems less common in the African. Genetic and environmental factors which contribute to these differences require elucidation. On going collaborations with Queen's University of Belfast, University of Iowa and Utah, The University of Ghana Medical School are looking at genetic differences between the African and Caucasians in the pathogenesis of AMD.
研究兴趣
论文共 267 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Eyeno. 3 (2024): 578-584
Craig Wilde,Georgios D Panos, Ali Pooschti, Hamish K MacNab, Jonathan G Hillman,Stephen A Vernon,Winfried M Amoaku
Journal of Clinical Medicineno. 3 (2024): 739
Moussa A. Zouache, Caitlin D. Faust,Vittorio Silvestri, Stephen Akafo,Seth Lartey, Rajnikant Mehta,Joseph Carroll, Giuliana Silvestri,Gregory S. Hageman,Winfried M. Amoaku
OPHTHALMOLOGY SCIENCEno. 2 (2024): 100386-100386
Josephine Akpalu,Vera A Essuman,Winfried M Amoaku,Benjamin Abaidoo,Akye Essuman,Charles Hayfron-Benjamin, Nana A Barnes,Naa N Tagoe,George Asare,Thomas A Ndanu, Benedicta Appiah-Thompson, Imelda D-B Ofori-Adjei,
Ghana medical journalno. 2 (2023): 87-96
International Journal of Translational Medicineno. 1 (2023): 120-159
引用0浏览0引用
0
0
S.P. Sarda, J. Quilantan, C. Réaume,W. Amoaku, S. Quéré, M. M’Hari, J. Carpenter-Conlin,D.L. Jones, S. Bakri,J.S. Nielsen
引用0浏览0引用
0
0
Ophthalmic surgery, lasers & imaging retinano. 10 (2023): 589-598
Drug design, development and therapy (2023): 2861-2873
引用0浏览0WOS引用
0
0
Journal of advanced pediatrics and child healthno. 1 (2023): 014-021
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn