The personal experience of losing my younger brother to metastatic cancer led to a long career in translational cancer research. I am one of the European pioneers in cancer immunotherapy with a focus on prostate cancer and urothelial cancers. Over 200 publications appeared in peer review journals (HI-index > 50). Oral presentations were given at ASCO, ESMO, and other international meetings. I participated in internal advisory boards regularly. Reviewer for Dutch CancerFoundation, CRUK ( 9 years), and multiple journals.