His career centered on imaging ionizing radiation, including nuclear medical imaging (especially Positron Emission Tomography or PET), homeland security, subatomic particle physics, and environmental remediation.
He has led research groups for over 20 years, been principal investigator on 40 competitive research grants, advised 18 graduate students, and headed the Structural Biology and Imaging Department, which has 135 employees, students, and affiliates. He has over 220 peer-reviewed publications, over 110 invited presentations, and has served on advisory boards for the National Institutes of Health, the US Department of Energy, homeland security agencies, and several major universities