Dr. Whitcomb is a Professor of Medicine Emeritus whose research program involves a pancreatic disease focus for modeling complex, multistep gene-environment interactive disorders requiring a precision medicine approach. Dr. Whitcomb's multicenter, genotype-phenotyping hereditary pancreatitis, and North American Pancreatitis Study II (NAPS2) programs, plus acute pancreatitis and pancreatic cancer studies using reverse engineering and predictive modeling approaches serve as a foundation and pathway for diseases in multiple organ systems. Dr Whitcomb also studies the pathophysiology of severe acute pancreatitis and pain genetics.