Chen Wang - University Hospital Essen

基本信息

Career Trajectory

Bio

I currently focus on translational research of mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) in ischemic stroke, for example, the therapeutical efficacy of MSC-EVs in ischemic stroke with comorbidities (e.g., age, sex, and hyperlipidemia), with a strong interest in studying the mechanism of action of MSC-EV anti-inflammation and immunomodulation in poststroke neuroprotection and neurorestoration.

Research Interests

Papers共 30 篇Author StatisticsCo-AuthorSimilar Experts

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Autophagy Hub-Protein P62 Orchestrates Oxidative, Endoplasmic Reticulum Stress, and Inflammatory Responses Post-Ischemia, Exacerbating Stroke Outcome

Xingyun Quan, Yukun Yang, Xiaolong Liu,Britta Kaltwasser, Matthias Pillath-Eilers,Bernd Walkenfort, Sylvia Voortmann,Ayan Mohamud Yusuf,Nina Hagemann,Chen Wang,Mike Hasenberg,Dirk M Hermann,Ulf Brockmeier

Redox biology (2025): 103700-103700

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Extracellular Vesicles Lay the Ground for Neuronal Plasticity by Restoring Mitochondrial Function, Cell Metabolism and Immune Balance

Dirk M Hermann,Chen Wang,Ayan Mohamud Yusuf,Josephine Herz,Thorsten R Doeppner,Bernd Giebel

Journal of cerebral blood flow and metabolism official journal of the International Society of Cerebral Blood Flow and Metabolismpp.271678X251325039-271678X251325039, (2025)

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Extracellular Vesicles Obtained from Hypoxic Mesenchymal Stromal Cells Induce Neurological Recovery, Anti-inflammation, and Brain Remodeling after Distal Middle Cerebral Artery Occlusion in Rats

Mihaela Abuzan,Roxana Surugiu,Chen Wang,Ayan Mohamud-Yusuf,Tobias Tertel,Bogdan Catalin,Thorsten R. Doeppner,Bernd Giebel,Dirk M. Hermann,Aurel Popa-Wagner

Translational Stroke Researchpp.1-14, (2024)

Cited2Views0WOSBibtex

Delayed DNase-I Administration but Not Gasdermin-D Inhibition Induces Hemorrhagic Transformation after Transient Focal Cerebral Ischemia in Mice

Dongpei Yin,Chen Wang,Vikramjeet Singh,Ali Ata Tuz, Thorsten R Doeppner,Matthias Gunzer,Dirk M Hermann

Stroke (2024)

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Stroke and Myocardial Infarction Induce Neutrophil Extracellular Trap Release Disrupting Lymphoid Organ Structure and Immunoglobulin Secretion

Ali A. Tuz,Susmita Ghosh, Laura Karsch,Dimitris Ttoouli, Sai P. Sata, Oezguer Ulusoy,Andreas Kraus, Nils Hoerenbaum, Jan-Niklas Wolf, Sabrina Lohmann,Franziska Zwirnlein, Viola Kaygusuz, Vivian Lakovic, Hannah-Lea Tummes,Alexander Beer, Markus Gallert,Stephanie Thiebes,Altea Qefalia,Zuelal Cibir, Medina Antler,Sebastian Korste,Elias Haj Yehia,Lars Michel,Tienush Rassaf,Britta Kaltwasser,Hossam Abdelrahman,Ayan Mohamud Yusuf,Chen Wang,Dongpei Yin, Lars Haeusler,Smiths Lueong,Mathis Richter,Daniel R. Engel,Martin Stenzel,Oliver Soehnlein,Benedikt Frank,Mialitiana Solo-Nomenjanahary,Benoit Ho-Tin-Noe,Jens T. Siveke,Matthias Totzeck,Daniel Hoffmann,Anika Grueneboom,Nina Hagemann,Anja Hasenberg,Jean-Philippe Desilles,Mikael Mazighi,Albert Sickmann,Jianxu Chen,Dirk M. Hermann,Matthias Gunzer,Vikramjeet Singh

Nature Cardiovascular Research（2024）

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Neutrophil extracellular traps melt Peyer’s patches following stroke and myocardial infarction

Ali Tuz,Susmita Ghosh, Markus Gallert,Dimitris Ttoouli, Sai Sata, Özgür Ulusoy,Andreas Kraus,Franziska Zwirnlein, Viola Kaygusuz, Vivian Lakovic,Alexander Beer,Altea Qefalia,Zülal Cibir, Medina Antler,Sebastian Korste,Lars Michel,Tienush Rassaf,Britta Kaltwasser,Hossam Abdelrahman,Ayan Mohamud-Yusuf,Chen Wang, Lars Haeusler,Smiths Lueong,Martin Stenzel,Oliver Soehnlein,Benedikt Frank,Martin Köhrmann Köhrmann,Jens Siveke,Matthias Totzeck,Daniel Hoffmann,Anika Grüneboom,Nina Hagemann,Anja Hasenberg,Albert Sickmann,Jianxu Chen,Dirk Hermann,Matthias Gunzer,Vikramjeet Singh

crossref（2023）

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Neurotoxicity of Ischemic Astrocytes Involves STAT3-mediated Metabolic Switching and Depends on Glycogen Usage

Mina Borbor,Dongpei Yin,Ulf Brockmeier,Chen Wang, Marius Doeckel,Matthias Pillath-Eilers,Britta Kaltwasser,Dirk M. Hermann,Egor Dzyubenko

Glia（2023）

Cited10Views0WOSBibtex

Proteomics Analyses of Five Potential Plasma-Derived Exosomal Biomarkers for Acute Myocardial Infarction

Shasha Xu, Yi Zhai,Chen Wang,Yang Zhang,Xiaowei Liu,Jianjun Jiang,Yafei Mi

openalex（2023）

Cited1Views0Bibtex

Neural Precursor Cell Delivery Induces Acute Post-Ischemic Cerebroprotection, but Fails to Promote Long-Term Stroke Recovery in Hyperlipidemic Mice Due to Mechanisms That Include Pro-Inflammatory Responses Associated with Brain Hemorrhages

Dongpei Yin,Chen Wang,Yachao Qi,Ya-Chao Wang,Nina Hagemann,Ayan Mohamud Yusuf,Egor Dzyubenko,Britta Kaltwasser,Tobias Tertel,Bernd Giebel,Matthias Gunzer,Aurel Popa-Wagner,Thorsten R. Doeppner,Dirk M. Hermann

JOURNAL OF NEUROINFLAMMATION（2023）

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Morphological Predictors of Neurological Deterioration in Patients with Acute Isolated Pontine Infarct

Chen Wang,Jianling Ji,Wanting Wang,Yujie Wang

Acta Neurologica Belgica（2023）

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