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Proteins are the most versatile among the various biological building blocks. However, the strength of proteins - their versatility and specific interactions - also complicates and hinders their systematic design and engineering. Our lab has been interested in exploiting the modular nature of protein domains to design synthetic complexes that can perform new biological functions across different length scales. By adding logical and stimuli responsive components into the design, smart protein complexes can be created to sense and adapt to the constantly changing cellular environments. Research in our laboratory is focused on the development of new synthetic biology tools in connecting exchangeable protein domains into functional devices for applications in biocatalysis, biosensing, and therapeutics.
Proteins are the most versatile among the various biological building blocks. However, the strength of proteins - their versatility and specific interactions - also complicates and hinders their systematic design and engineering. Our lab has been interested in exploiting the modular nature of protein domains to design synthetic complexes that can perform new biological functions across different length scales. By adding logical and stimuli responsive components into the design, smart protein complexes can be created to sense and adapt to the constantly changing cellular environments. Research in our laboratory is focused on the development of new synthetic biology tools in connecting exchangeable protein domains into functional devices for applications in biocatalysis, biosensing, and therapeutics.
研究兴趣
论文共 531 篇作者统计合作学者相似作者
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APL Bioengineeringno. 2 (2024): 026127-026127-17
Methods in molecular biology (Clifton, N.J.) (2024): 177-189
Current opinion in biotechnology (2024): 103070-103070
BIOTECHNOLOGY AND BIOENGINEERINGno. 1 (2024): 403-408
ACS CATALYSISno. 9 (2024): 7050-7051
Methods in molecular biology (Clifton, N.J.) (2024): 151-164
Hopen Yang,Wilfred Chen
ACS Synthetic Biologyno. 7 (2024): 2073-2080
Current opinion in biotechnology (2023): 102890-102890
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#Papers: 523
#Citation: 20943
H-Index: 75
G-Index: 130
Sociability: 7
Diversity: 3
Activity: 39
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