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Bio
Since 1992, I have supervised over 50 PhD and MRes students who have successfully defended their theses. Over the same period, I have mentored over 10 postdoctoral fellows. A significant milestone in my career was the publication of my authoritative book 'Fmoc Solid Phase Peptide Synthesis: A Practical Approach' in 2000, which soon became an international 'Peptide Chemist Bible'. In 2006, I organised and chaired the first Merck Biosciences/RSC-sponsored mini-symposium on 'Chemistry and Biology of Peptides'.
In the field of peptide chemistry, I was instrumental in the development of a series of unique multi-functional/orthogonally protected chemical reagents, e.g. novel 4-azalysine analogues, which facilitated the construction of hybrid and complex peptides. The Dde-based chemistry and chemical toolkits, ranging from amine- (Bycroft et al 1993, 1994, Nash et al 1996) and carboxy-protecting groups (Chan et al 1995) to novel tagging reagents and pseudoaromatic amino acids (Middleton et al 2004), which are now widely used by the biomedical and chemical community, were discovered and further developed in my laboratory.
In the field of peptide chemistry, I was instrumental in the development of a series of unique multi-functional/orthogonally protected chemical reagents, e.g. novel 4-azalysine analogues, which facilitated the construction of hybrid and complex peptides. The Dde-based chemistry and chemical toolkits, ranging from amine- (Bycroft et al 1993, 1994, Nash et al 1996) and carboxy-protecting groups (Chan et al 1995) to novel tagging reagents and pseudoaromatic amino acids (Middleton et al 2004), which are now widely used by the biomedical and chemical community, were discovered and further developed in my laboratory.
Research Interests
Papers共 111 篇Author StatisticsCo-AuthorSimilar Experts
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Philip Bardelang,Ewan J Murray,Isobel Blower, Sara Zandomeneghi,Alice Goode,Rohanah Hussain,Divya Kumari,Giuliano Siligardi,Katsuaki Inoue,Jeni Luckett,James Doutch,Jonas Emsley,
Frontiers in chemistry (2023): 1113885-1113885
Michael Taylor,Fabio Simoes, James Smith, Sivaneswary Genapathy,Anne Canning,Marina Lledos,Weng C. Chan,Chris Denning,David J. Scurr,Rory T. Steven,Steve J. Spencer,Alexander G. Shard,
Surface and Interface Analysisno. 4 (2022): 417-432
Francesco Saverio Tarantini,Mara Brunati, Anna Taravella, Lucia Carrano,Francesco Parenti,Kar Wai Hong,Paul Williams,Kok Gan Chan,Stephan Heeb,Weng C Chan
Tanya M Monaghan,Anna M Seekatz,Benjamin H Mullish, ClaudiaER Moore-Gillon,Lisa Dawson, Ammar Ahmed,Dina Kao,Weng C Chan
Access Microbiologyno. 1A (2019)
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