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Bio
Vishal Patel is a Principal Investigator and group lead for Advanced Chronic Liver Disease (ACLD) with a focus on the role of the oral and gut microbiome, at The Roger Williams Institute of Hepatology (Foundation for Liver Research). His lab also has work-streams investigating the role of circulating cell-free DNA and coagulation dysfunction in chronic liver failure syndromes, working with colleagues at King's, Groningen, Netherlands and collaborators at Hospital Clinic, Barcelona.
His clinical role is as a Consultant Hepatologist & Endoscopist with a focus on ACLD and portal hypertension driven complications at the Liver Unit, King’s College Hospital. He is an Honorary Reader in Hepatology within the School of Immunology & Microbial Sciences at King''s College London. He has tertiary centre training and experience at the Liver Unit at King's College Hospital where he is now a Consultant in complex hepatology, liver intensive care medicine and liver transplantation. He is a JAG accredited endoscopist and certified colonoscopy trainer with advanced upper and lower GI diagnostic and therapeutic endoscopy skills, including the management of refractory portal hypertensive bleeding.
Vishal is involved in several observational and interventional translational studies in chronic and acute liver failure syndromes, including acute alcoholic hepatitis and hepatic encephalopathy. He is Chief Investigator of the BOPPP trial (ClinicalTrials.gov ID: NCT03776955) which is National Institute for Health Research funded (£2.5 million) evaluating the effectiveness of non-selective beta-blockers in preventing variceal haemorrhage in patients with small oesophageal varices and cirrhosis. BOPPP is one of the largest trials in portal hypertension globally, aiming to recruit 740 patients at 55 UK sites with the trial set to run over a 7 year period, prolonged by the COVID pandemic. He has also been the recipient of the NIHR Clinical Research Network Greenshoots Award, and has secured Young Investigator funding from the Intensive Care Foundation and Association of Physicians (Great Britain & Ireland).
Vishal conducted an investigator initiated randomised clinical trial (‘RIFSYS’; ClinicalTrials.gov ID: NCT02019784) examining the mechanistic effects of Rifaximin in cirrhosis complicated by hepatic encephalopathy – outcomes published in Journal of Hepatology (Feb 2022). He is Principal Investigator at the lead site for the NIHR EME funded RCT of Faecal Microbiota Transplantation in Cirrhosis (‘PROMISE’) and is involved in the Horizon 2020 funded MICROB-PREDICT study (€15 million). Work is now focusing on the therapeutic modulation of the ‘oral-gut-liver axis’ in cirrhosis, particularly in an era of increasing antimicrobial resistance, in which his group has a particular interest in characterising the 'resistome' in ACLD.
He enjoys collaborating closely with colleagues within King's Health Partners (King's College Hospital and King's College London) and the wider UK and European hepatology and microbiome community. He is a member of the Gut Microbiota for Health Expert Panel (British Society for Gastroenterology Research Section), and BSG-BASL Liver Research Development Group, where national strategy for hepatology research is formulated.
ORCID: https://orcid.org/0000-0001-6616-3628
Publons: https://publons.com/researcher/3189257/vishal-c-patel/
ResearchGate: https://www.researchgate.net/profile/Vishal_Patel48
Research Interests
Papers共 13 篇Author StatisticsCo-AuthorSimilar Experts
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Heather Holyoak,Liam Gabb, Jasmine Lee, Beth MacKay, Georgina Osborne,Wendy Prentice,Vishal Patel,Brian Hogan,Mark McPhail, Alejandro Morocho
Joseph Delo, Eleni Maria Stamouli,Deborah Chong,Daniel Forton,Evangelos Triantafyllou,Vishal Patel,Arjuna Singanayagam
GUTno. SUPPL_3 (2023): A40-A41
Veena Ramachandran, Alejandro Esquivel Morocho, Daniel Robles Ortiz, Zoe Elliott, Siva Dwarampudi, Maria-Emanuela Maxan,Mussarat Rahim,Ane Zamalloa, Ivy Dai,Wendy Prentice,Charlotte Woodhouse, Michelle Cheung,
Abstracts (2022)
N. Vergis,V. Patel, K. Bogdanowicz, J. Czyzewska-Khan,F. Fiorentino, E. Day, M. Cross,N. Foster, E. Lord,R. Goldin,E. Forrest,M. Thursz
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Author Statistics
#Papers: 13
#Citation: 9
H-Index: 1
G-Index: 2
Sociability: 4
Diversity: 2
Activity: 10
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