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Bio
Our genome is constantly damaged at considerably high numbers per cell per day by spontaneous hydrolytic decay and by various endogenous and environmental agents. In addition, nucleotide insertion errors during DNA replication and the process of DNA repair itself constitute substantial sources of genome modifications. The preservation of the chemical structure and the original nucleotide sequence of the genome are essential for life. Thus, mechanisms have evolved in all living organisms to repair DNA lesions and to maintain genome stability and integrity.
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Papers共 617 篇Author StatisticsCo-AuthorSimilar Experts
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The journals of gerontology. Series A, Biological sciences and medical sciencesno. 4 (2024)
Cold Spring Harbor perspectives in medicineno. 1 (2024): a041193-a041193
crossref(2024)
Jae-Hyeon Park,Burcin Duan Sahbaz, Komal Pekhale,Xixia Chu,Mustafa N Okur,Mhamed Grati,Kevin Isgrig,Wade Chien, Elena Chrysostomou, Lauren Sullivan,Deborah L Croteau,Uri Manor,
Aging Biology (2024)
Jianfei Zhang,Zhiquan Li,Jiangbo Song,Lei Zhou, Xin Chen, Wen Ge, Tianyi Dong,Yuxin Luo,Ting Mao,Zheng Li,Duan Tan,Lene Juel Rasmussen,
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCESno. 4 (2024)
Alzheimer's & Dementiano. 6 (2024): 4212-4233
Xiuli Dan, Bing Yang,Ross A. McDevitt,Samuel A. Gray,Xixia Chu, Quia Claybourne,David M. Figueroa,Yongqing Zhang,Deborah L. Croteau,Vilhelm A. Bohr
Aging Cellno. 4 (2023)
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