Vijayaratnam Santhakumar - Neuroscience, Innovative Medicines & Early Development, AstraZeneca

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论文共 72 篇作者统计合作学者相似作者

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Enantioselective Protein Affinity Selection Mass Spectrometry (EAS-MS)

Xiaoyun Wang,Jianxian Sun,Shabbir Ahmad,Diwen Yang,Fengling Li, U Hang Chan,Hong Zeng,Conrad V Simoben,Scott Houliston,Aiping Dong,Albina Bolotokova,Elisa Gibson, Maria Kutera,Pegah Ghiabi,Ivan Kondratov, Tetiana Matviyuk,Alexander Chuprina, Danai Mavridi,Christopher Lenz,Andreas C Joerger, Benjamin D Brown, Richard B Heath, Wyatt W Yue, Lucy K Robbie,Tyler S Beyett,Susanne Müller,Stefan Knapp,Rachel Harding,Matthieu Schapira,Peter J Brown,Vijayaratnam Santhakumar,Suzanne Ackloo,Cheryl H Arrowsmith,Aled M Edwards,Hui Peng,Levon Halabelian

bioRxiv the preprint server for biology (2025)

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Probing the CRL4DCAF12 Interactions with MAGEA3 and CCT5 Di-Glu C-terminal Degrons

Germanna Lima Righetto,Yanting Yin,David M. Duda,Victoria Vu,Magdalena M. Szewczyk,Hong Zeng,Yanjun Li,Peter Loppnau, Tony Mei, Yen-Yen Li,Alma Seitova, Aaron N. Patrick,Jean-Francois Brazeau,Charu Chaudhry,Dalia Barsyte-Lovejoy,Vijayaratnam Santhakumar,Levon Halabelian

PNAS Nexusno. 4 (2024)

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A Resource to Enable Chemical Biology and Drug Discovery of WDR Proteins

Suzanne Ackloo,Fengling Li,Magda Szewczyk,Almagul Seitova,Peter Loppnau,Hong Zeng,Jin Xu,Shabbir Ahmad, Yelena A Arnautova, AJ Baghaie,Serap Beldar,Albina Bolotokova,Paolo A Centrella,Irene Chau,Matthew A Clark,John W Cuozzo, Saba Dehghani-Tafti,Jeremy S Disch,Aiping Dong, Antoine Dumas,Jianwen A. Feng,Pegah Ghiabi,Elisa Gibson,Justin Gilmer,Brian Goldman,Stuart R Green,Marie-Aude Guié,John P Guilinger,Nathan Harms, Oleksandra Herasymenko,Scott Houliston,Ashley Hutchinson,Steven Kearnes,Anthony D Keefe,Serah W Kimani,Trevor Kramer, Maria Kutera, Haejin A Kwak,Cristina Lento,Yanjun Li, Jenny Liu,Joachim Loup,Raquel AC Machado,Christopher J Mulhern,Sumera Perveen, Germanna L Righetto,Patrick Riley, Suman Shrestha,Eric A Sigel, Madhushika Silva, Michael D. Sintchak,Belinda L Slakman, Rhys D Taylor, James Thompson,Wen Torng, Carl Underkoffler,Moritz von Rechenberg,Ian Watson,Derek J Wilson,Esther Wolf, Manisha Yadav, Aliakbar K Yazdi,Junyi Zhang,Ying Zhang,Vijayaratnam Santhakumar,Aled M Edwards,Dalia Barsyte-Lovejoy,Matthieu Schapira,Peter J Brown,Levon Halabelian,Cheryl H Arrowsmith

biorxiv（2024）

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A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Suzanne Ackloo,Fengling Li,Magda Szewczyk,Almagul Seitova,Peter Loppnau,Hong Zeng,Jin Xu,Shabbir Ahmad, Yelena A. Arnautova, A. J. Baghaie,Serap Beldar,Albina Bolotokova,Paolo A. Centrella,Irene Chau,Matthew A. Clark,John W. Cuozzo, Saba Dehghani-Tafti,Jeremy S. Disch,Aiping Dong, Antoine Dumas,Jianwen A. Feng,Pegah Ghiabi,Elisa Gibson,Justin Gilmer,Brian Goldman,Stuart R. Green,Marie-Aude Guie,John P. Guilinger,Nathan Harms, Oleksandra Herasymenko,Scott Houliston,Ashley Hutchinson,Steven Kearnes,Anthony D. Keefe,Serah W. Kimani,Trevor Kramer, Maria Kutera, Haejin A. Kwak,Cristina Lento,Yanjun Li, Jenny Liu,Joachim Loup,Raquel A. C. Machado,Christopher J. Mulhern,Sumera Perveen, Germanna L. Righetto,Patrick Riley, Suman Shrestha,Eric A. Sigel, Madhushika Silva, Michael D. Sintchak,Belinda L. Slakman, Rhys D. Taylor, James Thompson,Wen Torng, Carl Underkoffler,Moritz von Rechenberg,Ryan T. Walsh,Ian Watson,Derek J. Wilson,Esther Wolf, Manisha Yadav, Aliakbar K. Yazdi, Junyi Zhang,Ying Zhang,Vijayaratnam Santhakumar,Aled M. Edwards,Dalia Barsyte-Lovejoy,Matthieu Schapira,Peter J. Brown,Levon Halabelian,Cheryl H. Arrowsmith

Journal of medicinal chemistryno. 2 (2024): 1092-1112

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Crystal Structures of DCAF1-PROTAC-WDR5 Ternary Complexes Provide Insight into DCAF1 Substrate Specificity

Mark F. Mabanglo,Brian Wilson, Mahmoud Noureldin,Serah W. Kimani,Ahmed Mamai, Chiara Krausser,Hector Gonzalez-Alvarez, Smriti Srivastava,Mohammed,Laurent Hoffer,Manuel Chan, Jamie Avrumutsoae,Alice Shi Ming Li,Taraneh Hajian, Sarah Tucker, Stuart Green,Magdalena Szewczyk,Dalia Barsyte-Lovejoy,Vijayaratnam Santhakumar,Suzanne Ackloo,Peter Loppnau,Yanjun Li,Almagul Seitova,Taira Kiyota, Jue George Wang,Gilbert G. Prive,Douglas A. Kuntz, Bhashant Patel, Vaibhavi Rathod,Anand Vala, Bhimsen Rout,Ahmed Aman,Gennady Poda,David Uehling, Jailall Ramnauth,Levon Halabelian,Richard Marcellus,Rima Al-Awar,Masoud Vedadi

NATURE COMMUNICATIONSno. 1 (2024)

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Development of Selective Class I Protein Arginine Methyltransferase Inhibitors Through Fragment-Based Drug Design Approach

Debomita Bhattacharya,Alice Shi Ming Li,Barnali Paul,Uddipta Ghosh Dastidar,Vijayaratnam Santhakumar,Dipika Sarkar,Irene Chau,Fengling Li,Trisha Ghosh,Masoud Vedadi,Arindam Talukdar

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2023)

引用5浏览0WOS引用

Discovery of a First-in-class Small Molecule Ligand for WDR91 Using DNA-encoded Chemical Library Selection Followed by Machine Learning

Journal of Medicinal Chemistryno. 23 (2023): 16051-16061

引用2浏览0WOS引用

Probing the Mechanism of Cbl-b Inhibition by a Small-Molecule Inhibitor

Serah Kimani,Sumera Perveen, Magdalena Szewezyk,Hong Zeng,Aiping Dong,Fengling Li,Pegah Ghiabi,Yanjun Li,Irene Chau,Cheryl Arrowsmith,Dalia Barsyte-Lovejoy,Vijayaratnam Santhakumar,Masoud Vedadi,Levon Halabelian

bioRxiv (2023)

引用3浏览0引用

Discovery of Nedd4 Auto-Ubiquitination Inhibitors

Darren Yong,Stuart R. Green,Pegah Ghiabi,Vijayaratnam Santhakumar,Masoud Vedadi

SCIENTIFIC REPORTSno. 1 (2023)

引用1浏览0WOSNATURE引用

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