基本信息
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Career Trajectory
Bio
Meet Dr. Pidugu, an accomplished cancer biologist with expertise in Cancer Biology, 3D-Cancer Organoids, CRISPR Genome editing, Molecular target discovery, and Preclinical toxicology. He thrives in competitive and challenging environments and seeks to contribute his skills to progressive organizations. From a young age, Dr. Pidugu witnessed the suffering of those affected by cancer, inspiring his dedication to advancing technologies in cancer biology. He aims to identify the fundamental molecular and genetic errors of the disease and develop molecular interventions to correct them, ultimately reducing mortality rates.
During his Ph.D., Dr. Pidugu studied the oncogenic role of IFIT1 and IFIT3 in oral squamous cell carcinoma metastasis and drug resistance mechanisms using cell and animal models. He is currently working with Dr. Ji Luo at the National Cancer Institute, NIH, USA, where he is investigating mutant Kras-driven lung adenocarcinoma progression and drug resistance mechanisms. His innovative approach involves developing a multiplex CRISPR-Cas9-based genome engineering technique combined with a robust 3D alveolar epithelial type 2 cells (AEC-2)-derived lung organoids platform to model dynamics of multiple molecular subtypes of lung adenocarcinoma.
Dr. Pidugu has published numerous research articles, reviews, and editorials in peer-reviewed international journals and received many national and international awards for his research. He also works as an academic reviewer and associate editor for several international journals. In his spare time, Dr. Pidugu enjoys watching movies, playing with his child, training at the gym, hiking, and traveling.
Research Interests
Papers共 22 篇Author StatisticsCo-AuthorSimilar Experts
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Frontiers in Endocrinology (2023): 1292619
Frontiers in endocrinology (2023): 1235274-1235274
Genomicsno. 5 (2019): 1108-1114
Proceedings for Annual Meeting of The Japanese Pharmacological Societyno. 0 (2018): PO4-6
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