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The research work in my laboratory focuses on identifying novel immunotherapeutic targets for the treatment of brain tumors, specifically glioblastoma (GBM). My previous work includes the development of the dual-specific immunotoxin (IT) D2C7-IT, which is currently in Phase I clinical trials in recurrent GBM (rGBM) patients. My current research seeks to identify novel strategies to enhance the efficacy of D2C7-IT and other GBM-targeted cytotoxic therapies. In conjunction with this, my research includes the investigation of immune-related biomarkers to predict the clinical outcome of D2C7-IT therapy in patients with GBM.
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论文共 45 篇作者统计合作学者相似作者
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PLOS ONEno. 3 (2024): e0299820-e0299820
Annick Desjardins,Vidya Chandramohan,Daniel Landi, Katherine B. Peters,Margaret Johnson,Justin Low,Mustafa Khasraw, Stevie Threatt,Chevelle Bullock,James E. Herndon,Eric Lipp,Allan H. Friedman,
Neuro-oncologyno. Supplement_5 (2023): v62-v63
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Neuro-oncologyno. Supplement_5 (2023): v233-v233
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biorxiv(2023)
Science Translational Medicineno. 682 (2023)
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Neuro-Oncology Advancesno. Supplement_1 (2022)
Neuro-Oncologyno. Supplement_7 (2022): 65-65
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