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个人简介
A major focus of Dr. Ling’s research has been the investigation of mechanisms of drug resistance to anticancer drugs, particularly those mechanisms that involve alteration in the transport of such compounds. On-going research includes site-directed mutagenesis to specifically alter structure, purification and reconstitution of P-glycoprotein to investigate function and structural studies using biophysical techniques. At the clinical level, research is ongoing to determine if the P-glycoprotein mechanism may be manipulated to improve efficacy. His laboratory is also investigating the structure and function of the superfamily of P-glycoprotein-like transporter proteins, ABC transporters in various species. Dr. Ling’s work to date has been documented in over 200 peer-reviewed publications.
研究兴趣
论文共 139 篇作者统计合作学者相似作者
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Jing Yang, Ya-Nan Zhang,Ren-Xue Wang, Chen-Zhi Hao,Yiling Qiu, Hao Chi, Wei-Sha Luan, HongYi Tang,Xiu-Juan Zhang, XuXu Sun, Jonathan A Sheps,Victor Ling,
Journal of medical geneticsno. 8 (2024): 750-758
Teng Liu,Ren-Xue Wang, Jun Han,Zhong-Die Li,Jonathan A. Sheps,Li -Juan Zheng, Xiao-Xiao Xu,Victor Ling,Jian-She Wang
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGYno. 2 (2024): 151-161
Journal of clinical and translational hepatologyno. 2 (2023): 151-161
Gene Amplification in Mammalian Cellspp.71-84, (2020)
Gene Amplification in Mammalian Cellspp.287-300, (2020)
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