基本信息
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Bio
The DDL team consists of accomplished scientists and skilled technicians from multiple scientific disciplines who have joined the lab to find effective, safe therapeutics for the treatment of neurodegenerative disease, with a focus on Alzheimer's disease. Led by Varghese John, Ph.D, the team works together to conduct most aspects of preclinical drug discovery, from development of phenotypic screens and target validation, to medicinal chemistry for hit-to-lead optimization, in vitro ADME-T studies for lead advancement, in vivo pharmacokinetic and pharmacodynamic testing for target engagement, and lead confirmation.
Research Interests
Papers共 162 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
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期刊级别
合作者
合作机构
Journal of Neuroscience Methods (2024): 110137-110137
TETRAHEDRON LETTERS (2024): 154961
Bruce Teter,Jesus Campagna,Chunni Zhu, Grace E. McCauley,Patricia Spilman,Donald B. Kohn,Varghese John
biorxiv(2024)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
bioRxiv the preprint server for biology (2023)
Research Square (Research Square) (2022)
Archives of Clinical and Biomedical Researchno. 06 (2022)
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Author Statistics
#Papers: 163
#Citation: 6062
H-Index: 33
G-Index: 74
Sociability: 6
Diversity: 2
Activity: 16
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