基本信息
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Bio
The study and implementation of “accuracy” is the general theme unifying the different components of my research program. Accuracy of the translation process with the study of the role of tRNA modifications in cellular physiology. Accuracy of metabolism with the discovery of novel mechanisms of metabolite repair. Finally, accuracy of annotations with my constant preoccupation on improving functional annotations of genomes.
Another common thread that links the different research projects in my laboratory is the use of comparative genomic and experimental methods to link gene and function (summarized in the figure below) that has allowed us to discover the function of over fifty protein families covering several hundred thousand individual genes in the last fifteen years. This in silicodriven approach has also placed me at the interface between the computer and experimental sciences and between the classical genetic and biochemical communities and the bioinformatic and annotation ones.
Another common thread that links the different research projects in my laboratory is the use of comparative genomic and experimental methods to link gene and function (summarized in the figure below) that has allowed us to discover the function of over fifty protein families covering several hundred thousand individual genes in the last fifteen years. This in silicodriven approach has also placed me at the interface between the computer and experimental sciences and between the classical genetic and biochemical communities and the bioinformatic and annotation ones.
Research Interests
Papers共 158 篇Author StatisticsCo-AuthorSimilar Experts
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biorxiv(2024)
bioRxiv : the preprint server for biology (2024)
Claudia Sudol, Lea-Marie Kilz,Virginie Marchand, Quentin Thullier,Vincent Guérineau,Catherine Goyenvalle,Bruno Faivre,Sabrine Toubdji,Murielle Lombard,Olivier Jean-Jean,Valérie de Crécy-Lagard,Mark Helm,
Nucleic acids researchno. 10 (2024): 5880-5894
Jingjing Sun,Junzhou Wu,Yifeng Yuan, Leon Fan, Wei Lin Patrina Chua, Yan Han Sharon Ling,Seetharamsing Balamkundu, D Dwijapriya, Suen,Valerie de Crecy-Lagard,Agnieszka Dziergowska,Peter Dedon
biorxiv(2024)
Samia Quaiyum,Yifeng Yuan,Guangxin Sun, R M Madhushi N Ratnayake,Geoffrey Hutinet,Peter C Dedon,Michael F Minnick,Valérie de Crécy-Lagard
bioRxiv : the preprint server for biology (2024)
bioRxiv the preprint server for biology (2023)
NUCLEIC ACIDS RESEARCHno. 21 (2023): 11980-11980
Liang Cui, Seetharamsingh Balalkundu,Chuanfa Liu,Hong Ye,Jacob Hourihan, Astrid Rausch,Christopher Hauß,Emelie Nilsson,Matthias Hoetzinger,Karin Holmfeldt,Weijia Zhang,Laura Martinez-Alvarez,
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Author Statistics
#Papers: 159
#Citation: 9932
H-Index: 54
G-Index: 96
Sociability: 7
Diversity: 4
Activity: 79
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