基本信息
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Bio
The study and implementation of “accuracy” is the general theme unifying the different components of my research program. Accuracy of the translation process with the study of the role of tRNA modifications in cellular physiology. Accuracy of metabolism with the discovery of novel mechanisms of metabolite repair. Finally, accuracy of annotations with my constant preoccupation on improving functional annotations of genomes.
Another common thread that links the different research projects in my laboratory is the use of comparative genomic and experimental methods to link gene and function (summarized in the figure below) that has allowed us to discover the function of over fifty protein families covering several hundred thousand individual genes in the last fifteen years. This in silicodriven approach has also placed me at the interface between the computer and experimental sciences and between the classical genetic and biochemical communities and the bioinformatic and annotation ones.
Another common thread that links the different research projects in my laboratory is the use of comparative genomic and experimental methods to link gene and function (summarized in the figure below) that has allowed us to discover the function of over fifty protein families covering several hundred thousand individual genes in the last fifteen years. This in silicodriven approach has also placed me at the interface between the computer and experimental sciences and between the classical genetic and biochemical communities and the bioinformatic and annotation ones.
Research Interests
Papers共 73 篇Author StatisticsCo-AuthorSimilar Experts
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Marshall Jaroch,Guangxin Sun,Ho-Ching Tiffany Tsui,Colbie Reed,Jingjing Sun, Marko Jörg,Malcolm E Winkler,Kelly C Rice, Agnieszka Dziergowska,Troy A Stich,Peter C Dedon,Patricia C Dos Santos,
Journal of bacteriologyno. 4 (2024): e0045223-e0045223
Samia Quaiyum,Yifeng Yuan,Guangxin Sun, R M Madhushi N Ratnayake,Geoffrey Hutinet,Peter C Dedon,Michael F Minnick,Valérie de Crécy-Lagard
bioRxiv : the preprint server for biology (2024)
FRONTIERS IN MICROBIOLOGY (2024): 1369018-1369018
bioRxiv the preprint server for biology (2023)
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