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The main goal of my research is development of methodology for radionuclide diagnostics and therapy of malignant tumours.
Main focus is currently on receptor tyrosine kinases (RTK) as molecular targets. Aberrant expression of RTKs is a part of malignant phenotype. Non-invasive radionuclide imaging of RTK expression provides important prognostic, predictive and pharmacodynamics information, making cancer treatment more personalised.
My main strategy is development of peptide-based tracers labelled with radionuclides.
Other strategies (e.g. the use of tumour-seeking small molecules, pre-targeting or combined systems) for delivery of radionuclides to tumour lesions may be considered for particular projects.
Main focus is currently on receptor tyrosine kinases (RTK) as molecular targets. Aberrant expression of RTKs is a part of malignant phenotype. Non-invasive radionuclide imaging of RTK expression provides important prognostic, predictive and pharmacodynamics information, making cancer treatment more personalised.
My main strategy is development of peptide-based tracers labelled with radionuclides.
Other strategies (e.g. the use of tumour-seeking small molecules, pre-targeting or combined systems) for delivery of radionuclides to tumour lesions may be considered for particular projects.
Research Interests
Papers共 749 篇Author StatisticsCo-AuthorSimilar Experts
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Biomedicinesno. 5 (2024): 1088
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING (2024): 107861-107861
Aleksei E. Machulkin, Stanislav A. Petrov, Vitalina Bodenko, Mariia S. Larkina, Evgenii Plotnikov, Feruza Yuldasheva, Maria Tretyakova, Ekaterina Bezverkhniaia, Nikolay Yu. Zyk, Elena Stasyuk, Roman Zelchan,Alexander G. Majouga,
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCEno. 5 (2024): 1457-1473
Sergey M. Deyev,Maryam Oroujeni,Javad Garousi,Torbjoern Graeslund, Ruonan Li, Alia Hani Binti Rosly,Anna Orlova,Elena Konovalova,Alexey Schulga,Anzhelika Vorobyeva,Vladimir Tolmachev
Panagiotis Kanellopoulos, Adam Mattsson,Ayman Abouzayed, Karim Obeid,Berthold A. Nock,Vladimir Tolmachev,Theodosia Maina,Anna Orlova
EJNMMI Radiopharmacy and Chemistryno. 1 (2024): 1-19
Kristina Westerlund,Maryam Oroujeni,Maxime Gestin, Jacob Clinton, Alia Hani Rosly,Hanna Tano,Anzhelika Vorobyeva,Anna Orlova,Amelie Eriksson Karlström,Vladimir Tolmachev
ACS Pharmacology & Translational Science (2024)
EJNMMI RADIOPHARMACY AND CHEMISTRYno. 1 (2024): 30-30
Panagiotis Kanellopoulos,Ekaterina Bezverkhniaia,Ayman Abouzayed, Ulrika Rosenstro''m,Vladimir Tolmachev,Anna Orlova
ACS OMEGAno. 16 (2024): 18608-18616
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