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We use integrated preclinial and clinical investigations to determine the contribution of the tumor reprogramed immune microenvironments in lung cancer and breast cancer. We are investigating modalities including subablative radiation and agents that target T cell dysfunction, endoplasmic stress as potent immunomodulators to enhance to the efficacy of immune checkpoint inhibitors. Our goals are to elucidate mechanistic insights into combination treatment, identify cellular and molecular biomarkers that predict major pathologic responders from non-responders, and identify clinically relevant targets for developing novel immunotherapies.
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论文共 243 篇作者统计合作学者相似作者
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Cell reports. Medicineno. 3 (2024): 101438-101438
Tatiana Delgado Cruz, Yanping Yang, Rachel Honigsberg,Geoffrey Markowitz,Nasser K Altorki,Vivek Mittal,Moonsoo M. Jin,Jonathan Villena-Vargas
Cancer Researchno. 6_Supplement (2024): 2-2
Yongfeng He, Sijin Luo Zhong,Bhavneet Bhinder,Geoffrey Markowitz, Arshdeep Singh,Eric Gardner, Myung Soo Ko,Nasser K. Altorki, Shaoyi Jiang,Vivek Mittal
Cancer Researchno. 6_Supplement (2024): 4097-4097
Cancer Researchno. 6_Supplement (2024): 6244-6244
Albert S. Agustinus, Duaa Al-Rawi, Bhargavi Dameracharla,Ramya Raviram, Bailey S. Jones, Stephanie Stransky,Lorenzo Scipioni,Jens Luebeck, Melody Di Bona, Danguole Norkunaite,Robert M. Myers, Mercedes Duran,
Cancer Researchno. 6_Supplement (2024): 4293-4293
Prue N. Plummer,Ruth Freeman,Ryan J. Taft,Jelena Vider,Michael Sax, Brittany A. Umer,Dingcheng Gao, Christopher Johns,John S. Mattick,Stephen D. Wilton,Vito Ferro,Nigel A.J. McMillan,
crossref(2023)
Nasser K Altorki, Zachary H Walsh,Johannes C Melms, Jeffery L Port,Benjamin E Lee,Abu Nasar,Cathy Spinelli,Lindsay Caprio,Meri Rogava,Patricia Ho,Paul J Christos,Ashish Saxena,
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Cancer Researchno. 7_Supplement (2023): 5884-5884
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