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Bio
Professor John Upham is a clinical scientist and respiratory physician at the University of Queensland Diamantina Institute and Princess Alexandra Hospital. Their research work aims to understand susceptibility to virus infections in severe asthma and the mechanisms leading to asthma exacerbations.
Current projects aim to establish and validate clinical and molecular characteristics of the ‘frequent exacerbator phenotype’, and the role of innate anti-viral interferons and dysregulation in the IL-33 signalling pathway. Through this work, it is anticipated research outcomes could deliver positive impacts for severe asthma patients, health care professionals and systems of care.
Current projects aim to establish and validate clinical and molecular characteristics of the ‘frequent exacerbator phenotype’, and the role of innate anti-viral interferons and dysregulation in the IL-33 signalling pathway. Through this work, it is anticipated research outcomes could deliver positive impacts for severe asthma patients, health care professionals and systems of care.
Research Interests
Papers共 397 篇Author StatisticsCo-AuthorSimilar Experts
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Chest (2024)
H. Scott,L.G. Wood,R. Callister,J.W. Upham,C.L. Grainge, S. Anderson, L.M. Williams, R.F. McLoughlin, E.J. Williams,S.R. Valkenborghs
C94. ASTHMA QUALITY IMPROVEMENT, HEALTH SERVICES RESEARCH, AND DISPARITIES (2024)
Ghislaine Scelo,Trung N Tran, Tham T Le,Malin Fagerås,Delbert Dorscheid,John Busby,Mona Al-Ahmad,Riyad Al-Lehebi,Alan Altraja, Aaron Beastall,Celine Bergeron,Leif Bjermer,
The journal of allergy and clinical immunology. In practice (2024)
H. Scott,L.G. Wood, R. Callister,J.W. Upham,C.L. Grainge, S. Anderson, L.M. Williams, R.F. McLoughlin, E.J. Williams, S.R. Valkenborghs
D101. UNCOVERING THE METABOLIC AND GENETIC UNSOLVED MYSTERIES IN ASTHMA (2024)
American journal of respiratory and critical care medicine (2024)
Hing C Kok,Gabrielle B McCallum,Stephanie T Yerkovich,Keith Grimwood,Siew M Fong,Anna M Nathan,Catherine A Byrnes,Robert S Ware, Nachal Nachiappan,Noorazlina Saari,Peter S Morris,Tsin W Yeo,
The Pediatric infectious disease journal (2024)
Sarah R Valkenborghs,Lisa G Wood,Robin Callister,John W Upham, Christopher L Grainge, Sophie Anderson, Lily M Williams,Rebecca F McLoughlin,Evan J Williams,Hayley A Scott
The journal of allergy and clinical immunology. In practice (2024)
Chinthaka Bhagya Samaranayake,John Upham,Khoa Tran,Luke S. Howard, Sean Nguyen, Myo Lwin,James Anderson,Sudhir Wahi,Laura C. Price,Stephen Wort,Wei Li,Colm McCabe,
BMJ OPEN RESPIRATORY RESEARCHno. 1 (2023): e001637-e001637
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