In the early 1970s, Amaldi co-discovered the proton-proton rising cross-section through experiments carried out at the CERN accelerator Intersecting Storage Rings. In 1975 he founded with K. Winter the CHARM Collaboration, which performed many fundamental experiments on neutrino scattering. In 1991, using the first LEP data he gave a widely recognized contribution to the understanding of the unification of the electroweak and strong forces.