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Bio
I am a protein biochemist qualified at doctoral level (PhD). My main expertise are in the combined fields of applied biochemistry, structural biology and recombinant production and characterisation of biologics, including reagent proteins, vaccines, enzymes and antibodies. In recent years my R&D focus has been on developing plant-based (N. benthamiana) and microbial (E. coli) fermentation production processes for biologics manufacture at bench (and for some markets, at pilot and commercial) scale, with an emphasis on downstream processing aspects. I have expert knowledge of these production systems as well as filtration and chromatography unit operations as applied to biomanufacturing process development at these scales. In my current environment as Research Group Leader at CSIR’s Biosciences unit, my main expected tangible output is in the form of technology demonstrators at a maturity of technology readiness level (TRL) of 5 – 6. At the same time, I continue to pursue an applied research program towards the production and characterisation of biologics, enzymes and reagent proteins (antibodies and metagenome-derived DNA manipulating enzymes). I also supervise a team of about 15 postgraduate students and scientific/technical staff and occasionally lecture and act as an examiner at Universities.
Research Interests
Papers共 37 篇Author StatisticsCo-AuthorSimilar Experts
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MICROORGANISMSno. 3 (2024): 570
Concepts and Strategies in Plant Sciences Applications of Plant Molecular Farmingpp.455-486, (2024)
crossref(2023)
Heliyonno. 6 (2023): e16723-e16723
crossref(2023)
Lindiwe Khumbuzile Zuma, Nothando Lovedale Gasa, Xolani Mazibuko,Mthokozisi Blessing C Simelane,Priyen Pillay,Lusisizwe Kwezi,Tsepo Tsekoa,Ofentse Jacob Pooe
Bacilli in Climate Resilient Agriculture and BioprospectingBacilli in Agrobiotechnologypp.101-126, (2022)
Social Science Research Network (2022)
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