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个人简介
Tríona Ní Chonghaile joined the Physiology and Medical Physics Department in the Royal College of Surgeons in Ireland, in 2015. She was recruited under the Strategic Academic Recruitment program (StAR), as a Research Lecturer and became a tenured Lecturer in 2018. She completed her PhD in Biochemistry in 2008, with Prof. Afshin Samali, at the National University of Ireland, Galway. She had an interest in translational science and moved to the Dana-Farber Cancer Institute/Harvard Medical School to do a postdoc with Prof. Anthony Letai, which was funded in part by a Multiple Myeloma Research Foundation Fellowship. In 2014, she moved back to Ireland and joined Prof. William Gallagher’s group as a Research Fellow working on identifying novel therapeutics for triple negative breast cancer.
Dr. Ní Chonghaile’s lab (www.ttc-lab.com) is interested in understanding why certain cancers are sensitive to chemotherapy induced cell death while others are resistant and how best to treat resistant cancers. She has a particular interest in the BCL-2 family of proteins that regulate the mitochondrial cell death pathway. She uses an innovative technology called “BH3 profiling”, which was developed in Prof. Letai's lab, to functionally interrogate the cell death signalling in both leukaemia and breast cancers to identify novel effective combinations of treatments. Based on her work, she received the European Association of Cancer Research (senior) young scientist of the year award (2014), along with receiving the prestigious L’Oréal-UNESCO For Women in Science UK&I Fellowship (2015). Her research is funded by grants from SFI-HRB-Wellcome Trust, H2020 and Breast Cancer Now. She has published in high-impact journals including Science, Cancer Discovery & Science Advances.
研究兴趣
论文共 98 篇作者统计合作学者相似作者
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Binbin Gao,Elspeth Ward,Anna Blümel,Emer Conroy, Rachel Moore, Grainne Cremin,Rachel Bleach, Kathryn Haley,Tríona Ní Chonghaíle,Andreas Lindner,Jochen Prehn,Yi Zhang,
Cancer Researchno. 9_Supplement (2024): PO3-18
Lyndsey Flanagan, Aisling Coughlan,Nicola Cosgrove,Andrew Roe, Yu Wang, Stephanie Gilmore, Izabela Drozdz,Claire Comerford,Jeremy Ryan, Emma Minihane,Salma Parvin, Michael O'Dwyer,
Haematologicano. 1 (2024)
Santi Suryani, Hernan Carol,Triona Ni Chonghaile, Viktoras Frismantas, Chintanu Sarmah, Laura High, Beat Bornhauser, Mark J. Cowley, Barbara Szymanska, Kathryn Evans, Ingrid Boehm, Elise Tonna,
crossref(2023)
CHEMICAL COMMUNICATIONSno. 84 (2023): 12641-12644
Bo Li,Triona Ni Chonghaile,Yue Fan, Stephen F. Madden,Rut Klinger, Aisling E. O'Connor,Louise Walsh, Gillian O'Hurley,Girish Mallya Udupi,Jesuchristopher Joseph,Finbarr Tarrant,Emer Conroy,
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Hua Zhang, Christopher S. Nabel, Dezhi Li, Ruth Í. O’Connor, Caroline R. Crosby,Sarah M. Chang,Yuan Hao, Robyn Stanley,Soumyadip Sahu,Daniel S. Levin,Ting Chen, Sittinon Tang,
Journal of Thoracic Oncology (2023)
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