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个人简介
Research Summary
I am a medical oncologist with a PhD in cell and molecular biology. I maintain an active academic clinical practice and lead a basic and translational research laboratory focused on cancer genetics, precision medicine, and the molecular basis of targeted therapy response and resistance. I have discovered several mechanisms of resistance to EGFR-targeted therapy, BRAF- and MEK-targeted therapy, and ALK-targeted therapy in lung and other cancers. I direct a multi-disciplinary team engaged in laboratory-based patient-focused research, and I am an investigator on clinical trials, including rational upfront polytherapy trials designed to forestall and eliminate resistance and that are motivated by my laboratory-based discoveries.
I am a medical oncologist with a PhD in cell and molecular biology. I maintain an active academic clinical practice and lead a basic and translational research laboratory focused on cancer genetics, precision medicine, and the molecular basis of targeted therapy response and resistance. I have discovered several mechanisms of resistance to EGFR-targeted therapy, BRAF- and MEK-targeted therapy, and ALK-targeted therapy in lung and other cancers. I direct a multi-disciplinary team engaged in laboratory-based patient-focused research, and I am an investigator on clinical trials, including rational upfront polytherapy trials designed to forestall and eliminate resistance and that are motivated by my laboratory-based discoveries.
研究兴趣
论文共 279 篇作者统计合作学者相似作者
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biorxiv(2024)
Nature cancerno. 6 (2024): 938-952
Donghwa Kim,Dmitry Kuchenov,Aubhishek Zaman,Neal Bennett, Emilio Ramos,Ken Nakamura, Arun P. Wiita,Sourav Bandyopadhyay,Trever Bivona
Cancer Researchno. 6_Supplement (2024): 4653-4653
Cancer Researchno. 6_Supplement (2024): 2006-2006
medrxiv(2024)
Clinical Lung Cancer (2024)
CANCER DISCOVERYno. 4 (2024): 630-634
Nature communicationsno. 1 (2024): 4871-4871
Collin M Blakely,Anatoly Urisman, Matthew A Gubens,Claire K Mulvey,Greg M Allen, Stephen C Shiboski,Julia K Rotow, Turja Chakrabarti,D Lucas Kerr,Jacqueline V Aredo, Bianca Bacaltos, Megan Gee,
Journal of clinical oncology : official journal of the American Society of Clinical Oncologypp.JCO2400071-JCO2400071, (2024)
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