Zheng has been conducting epidemiological research as Principal Investigators in the areas of cancer epidemiology and environmental epidemiology investigating the relationship between environmental exposures, genetic polymorphisms, epigenetic factors and gene-environment interaction in the risk of various cancers in the US and in China, including breast cancer; non-Hodgkin’s lymphoma, Hodgkin’s disease, multiple myeloma, liver cancer, thyroid cancer, lung cancer and testis cancer. Dr. Zheng has authored or co-authored over 380 articles/book chapters and co-edited the textbook, Epidemiology and Biostatistics. He has been leading two Fogarty training programs in China training and conducting collaborated epidemiological studies in China.