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个人简介
Tim is an Associate Professor and Wellcome Trust Career Development Fellow and leads the HinksLab. As an Honorary NHS Consultant in Respiratory Medicine he co-leads the Oxford Specialist Airways service, providing secondary and tertiary care for people with unstable, difficult and severe asthma at the John Radcliffe Hospital in Oxford.
Tim studied medicine at Cambridge and Oxford. He then researched novel T cell-based immunodiagnostics for tuberculosis as a research fellow in Oxford. In 2007 he moved to Wessex as an Academic Clinical Fellow to undertake higher clinical training in respiratory medicine. Funded by a Wellcome Training Fellowship his doctoral research in Southampton with Ratko Djukanovic and Stephan Gadola was into the roles of innate and adaptive T cells in the human airways in asthma. On a Wellcome Postdoctoral Clinical Fellowship with James McCluskey at the Peter Doherty Institute, University of Melbourne he researched the basic biology of mucosal associated invariant T cells in bacterial and viral respiratory infections and in tissue repair. Tim returned to Oxford in 2017 to establish his own group within the Respiratory Medicine Unit with core funding from the Wellcome Trust and Beit Fellowship.
The group’s current research focuses are defining the innate-like mucosal T cell response to bacterial infection in airways disease, specifically Haemophilus influenzae in severe asthma, investigating the immune mechanisms underlying macrolide efficacy in asthma, and studying the immunopathology of highly phenotyped asthma at genetic, epigenetic, transcriptomic and immunological levels. The group use a range of in vitro, in vivo and human ex vivo tools, including an active bronchoscopy-based research programme.
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biorxiv(2024)
EUROPEAN RESPIRATORY JOURNAL (2023)
Frontiers in immunology (2023): 1281881-1281881
Frontiers in Immunology (2023): 1127588
THORAXno. SUPPL_4 (2023): A73-A73
PLoS pathogensno. 5 (2023): e1011323-e1011323
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