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Timothy K. Lu(盧冠達)
Associate Professor
Department of Biological Engineering
Massachusetts Institute of Technology;Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology;Senti Biosciences;Engine Biosciences;Tango Therapeutics;BiomX;Winged Concepts;Synlogic, Inc.;Eligo Biosciences;Corvium
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基本信息
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Bio
Our research focuses on using synthetic biology and systems biology tools to engineer gene networks from the bottoms-up and to decipher natural gene networks from the top-down. We have developed high-throughput platforms for building and studying gene networks. These approaches have been applied to therapeutically relevant contexts. For example, we have engineered synthetic viruses to combat antibiotic resistant, genetically modified probiotics to treat inflammatory bowel disease in the gut, and next-generation viral therapies for cancer. In addition, we have used these technologies to study genetic interactions and potential targets for combinatorial therapy against antibiotic-resistant bacteria, cancer, and neurodegenerative diseases.
Research Interests
Papers共 295 篇Author StatisticsCo-AuthorSimilar Experts
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Nature Communicationsno. 1 (2024): 1-17
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
Alba Gonzalez, Enping Hong,Gozde Yucel, Elizabeth Leitner, Pearley Chinta,Han Deng, Ian Li,Alice Lam, Abla Bakir,Brandon Lee, Papia Chakraborty,Carmina Blanco,
CANCER RESEARCHno. 7 (2023)
Cancer cellno. 10 (2023): 1689-1695
Frances D. Liu,Michelle Hung,Assen Roguev,Yin Yin Chong, Eniola Catton, Jessica Haverkamp, Panos Douvaras, Alex Danza,Monika Avina,Mark Tomishima,Russell Gordley,Gary K. Lee,
MOLECULAR THERAPYno. 4 (2023): 722-723
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CANCER RESEARCHno. 7 (2023)
Philip Lee,Assen Roguev, Cesar Juarez,Michelle Hung,Frances D Liu,Yin Yin Chong,Russell M Gordley,Mark Tomishima, Jessica M Haverkamp, Panos Douvaras, Alex Danza,Monika Avina,
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
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