Tim Fryer

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My research concentrates on positron emission tomography (PET) methodology, with particular emphasis on the quantitative accuracy of the physiological parameters derived from the data. Current research themes are: parametric mapping using basis functions; spatio-temporal image reconstruction for kinetic analysis; direct parameter estimation; wavelet-based kinetic analysis; 4D motion compensated image reconstruction; MRI-based motion correction for PET/MRI scanners; image optimisation using automated observers; automated region-of-interest definition; attenuation correction for PET/MRI scanners.

Research Interests

Papers共 365 篇Author StatisticsCo-AuthorSimilar Experts

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Polygenic Risk Discriminates Lewy Body Dementia from Alzheimer's Disease

Anna Mckeever,Peter Swann,Maura Malpetti,Paul C. Donaghy,Alan Thomas,Elijah Mak,Stephen F. Carter, Jerry H. K. Tan,Young T. Hong,Tim D. Fryer,Amanda Heslegrave,Henrik Zetterberg,Li Su,Leonidas Chouliaras,James B. Rowe,John T. O'Brien

ALZHEIMERS & DEMENTIA（2025）

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Blood Inflammation Relates to Neuroinflammation and Survival in Frontotemporal Lobar Degeneration

Brain a journal of neurologyno. 2 (2025): 493-505

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A Novel Blood-Free Analytical Framework for the Quantification of Neuroinflammatory Load from TSPO PET Imaging

Lucia Maccioni,Ludovica Brusaferri, Leonardo Barzon,Julia J Schubert,Maria A Nettis,Oliver Cousins,Ivana Rosenzweig,Yuya Mizuno,Marta Vicente-Rodríguez,Nisha Singh, Tiago Reis Marques,Neil A Harrison,Tim Fryer,Edward T Bullmore,Diana Cash,Valeria Mondelli,Carmine Pariante,Oliver Howes,Federico E Turkheimer,Marco L Loggia,Mattia Veronese

Research square (2025)

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Extra-axial Inflammatory Signal and Its Relationship to Peripheral and Central Immunity in Depression

Brandi Eiff,Edward T. Bullmore,Menna R. Clatworthy,Tim D. Fryer,Carmine M. Pariante,Valeria Mondelli, Lucia Maccioni,Nouchine Hadjikhani,Marco L. Loggia,Michael A. Moskowitz, Emiliano Bruner,Mattia Veronese,Federico E. Turkheimer,Edward Thomas NIMA Consortium,Julia J. Schubert

Brain a journal of neurologyno. 2 (2025): 635-646

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Post-mortem Validation of in Vivo TSPO PET As a Microglial Biomarker

Sasvi S Wijesinghe,James B Rowe, Hannah D Mason,Kieren S J Allinson, Reuben Thomas, Davi S Vontobel,Tim D Fryer,Young T Hong,Mehtap Bacioglu,Maria Grazia Spillantini,Jelle van den Ameele,John T O'Brien, Sanne Kaalund,Maura Malpetti,Annelies Quaegebeur

Brain a journal of neurologyno. 6 (2025): 1904-1910

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MINocyclinE to Reduce Inflammation and Blood-Brain Barrier Leakage in Small Vessel Disease (MINERVA): A Phase II, Randomized, Double-Blind, Placebo-Controlled Experimental Medicine Trial

Robin B. Brown,Daniel J. Tozer,Laurence Loubiere,Eric L. Harshfield,Young T. Hong,Tim D. Fryer,Guy B. Williams,Martin J. Graves,Franklin I. Aigbirhio,John T. O'Brien,Hugh S. Markus

Alzheimer s & Dementiano. 6 (2024): 3852-3863

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Are Central and Systemic Inflammation Associated with Fatigue in Cerebral Small Vessel Disease

Amy A. Jolly,Robin B. Brown,Daniel J. Tozer,Young T. Hong,Tim D. Fryer,Franklin Aigbirhio,John T. O'Brien,Hugh S. Markus

INTERNATIONAL JOURNAL OF STROKEno. 6 (2024): 705-713

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Comparison of Reference Region Stability for Longitudinal Amyloid PET in Down Syndrome

Alzheimer's &amp Dementiano. S9 (2024)

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Connectivity As a Universal Predictor of Tau Spreading in Typical and Atypical Alzheimer’s Disease

Hannah de Bruin, Colin Groot,Henryk Barthel,Gérard N Bischof,Ronald Boellaard,Matthias Brendel,David M Cash,William Coath,Gregory S Day,Brad C Dickerson,Elena Doering,Alexander Drzezga,Christopher H. van Dyck,Thilo van Eimeren,Wiesje M. van der Flier,Carolyn Fredericks,Tim D Fryer,Elsmarieke van de Giessen,Brian A. Gordon,Jonathan Graff‐Radford,Diana A Hobbs,Günter Höglinger,Merle C Hönig,David J Irwin,P Simon Jones,Keith A. Josephs,Yuta Katsumi,Eddie B Lee,Johannes Levin,Maura Malpetti,Scott M McGinnis,Adam P Mecca,Ilya M. Nasrallah,John T O'Brien,Ryan S O'Dell,Carla Palleis,Robert Perneczky,Jeffrey S Phillips,Yolande A.L. Pijnenburg,Deepti Putcha,Nesrine Rahmouni,Pedro Rosa‐Neto,James B Rowe,Michael Rullmann,Osama Sabri,Dorothee Saur,Andreas Schildan,Jonathan M Schott,Matthias L Schroeter,Stijn Servaes,Irene Sintini,Jenna Stevenson,Joseph Therriault,Alexandra Touroutoglou, Anne E Trainer,Denise Visser,Philip SJ Weston,Jennifer L. Whitwell,David A Wolk,Nicolai Franzmeier,Rik Ossenkoppele

Alzheimer's &amp Dementiano. S9 (2024)

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OP02 Redefining the Resection Target for Glioblastomas – an IDEAL Stage 0 and 1 Study

Stephen Price,Roxanne Mayrand, Francesca Cozzi,Yizhou Wan,Kieren Allinson,Chao Li,Tim Fryer,Tomasz Matys

Oral Presentations (2024)

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Papers共 365 篇Author StatisticsCo-AuthorSimilar Experts