基本信息
浏览量:4
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
The Vierbuchen laboratory seeks to elucidate fundamental mechanisms governing the production of the myriad neuronal cell types required to build functioning neural circuits. To model these dynamic developmental processes, we direct the differentiation of mouse and human pluripotent stem cells into specific neuronal cell types in a dish. This reductionist system allows us to recapitulate neural tube patterning and neuronal differentiation under controlled conditions and at a scale that makes it possible to use genetic screens, genomics, and systems genetics to characterize the underlying cell signaling and gene regulatory processes with unprecedented resolution. In the long term, we will apply these insights to better understand the complex genetic underpinnings of psychiatric and neurodegenerative disease.
研究兴趣
论文共 24 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Moritz Mall,Michael S Kareta,Soham Chanda,Henrik Ahlenius, Nicholas Perotti,Bo Zhou,Sarah D Grieder,Xuecai Ge,Sienna Drake,Cheen Euong Ang, Brandon M Walker,Thomas Vierbuchen,
Natureno. 8017 (2024): E11-E11
Rachel A Glenn, Stephanie C Do, Karthik Guruvayurappan, Emily K Corrigan, Laura Santini, Daniel Medina-Cano, Sarah Singer, Hyein Cho,Jing Liu,Karl Broman, Anne Czechanski, Laura Reinholdt,
bioRxiv : the preprint server for biology (2024)
Nature geneticsno. 8 (2023): 1336-1346
Alissa J. Trzeciak,Waleska Saitz Rojas, Zong-Lin Liu, Adam S. Krebs,Zhaoquan Wang,Pedro H. V. Saavedra,Isabella C. Miranda, Allie Lipshutz,Jian Xie,Chou-Long Huang,Michael Overholtzer,Michael S. Glickman,
bioRxiv : the preprint server for biology (2023)
Daniel Medina-Cano, Emily K. Corrigan, Rachel A. Glenn, Mohammed T. Islam,Yuan Lin, Juliet Kim, Hyunwoo Cho,Thomas Vierbuchen
Development (2022)
Research Square (Research Square) (2022)
crossref(2022)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn