Thomas J Macartney - CXR Biosciences Limited

基本信息

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个人简介

Experienced and skilled molecular biologist interested in the continued improvement of gene targeting techniques and in the further development of targeted protein degradation methodologies

研究兴趣

论文共 56 篇作者统计合作学者相似作者

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Kinome Screening Identifies Integrated Stress Response Kinase EIF2AK1/HRI As a Negative Regulator of PINK1 Mitophagy Signaling

Pawan K Singh, Shalini Agarwal,Ilaria Volpi, Léa P Wilhelm, Giada Becchi, Andrew Keenlyside,Thomas Macartney,Rachel Toth,Adrien Rousseau,Glenn R Masson,Ian G Ganley,Miratul M K Muqit

Science advancesno. 19 (2025): eadn2528-eadn2528

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AMPK Associates with and Causes Fragmentation of the Golgi by Phosphorylating the Guanine Nucleotide Exchange Factor GBF1

Jordana B. Freemantle,Mhairi C. Towler,Emma R. Hudson,Thomas Macartney,Monika Zwirek, David J. K. Liu,David A. Pan,Sreenivasan Ponnambalam,D. Grahame Hardie

Journal of cell science（2024）

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The UFM1 E3 Ligase Recognizes and Releases 60S Ribosomes from ER Translocons

Linda Makhlouf,Joshua J. Peter,Helge M. Magnussen, Rohan Thakur,David Millrine,Thomas C. Minshull, Grace Harrison,Joby Varghese,Frederic Lamoliatte,Martina Foglizzo,Thomas Macartney,Antonio N. Calabrese,Elton Zeqiraj,Yogesh Kulathu

Nature（2024）

引用5浏览0WOSNATURE引用

The Histone Chaperone SPT2 Regulates Chromatin Structure and Function in Metazoa

Nature Structural & Molecular Biologyno. 3 (2024): 523-535

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NRBP1 Pseudokinase Binds to and Activates the WNK Pathway in Response to Osmotic Stress

Ramchandra Amnekar, Toby Dite,Pawel Lis, Sebastian Bell,Fiona Brown,Clare Johnson, Stuart Wilkinson,Samantha Raggett,Mark Dorward, Mel Wightman,Thomas Macartney,Renata F Soares,Frederic Lamoliatte,Dario R Alessi

biorxiv（2024）

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PROTAC-mediated Conditional Degradation of the WRN Helicase As a Potential Strategy for Selective Killing of Cancer Cells with Microsatellite Instability

Vikram Tejwani,Thomas Carroll,Thomas Macartney,Susanne Bandau,Constance Alabert,Giulia Saredi,Rachel Toth,John Rouse

Scientific Reports（2024）

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Chemo-phosphoproteomic Profiling with ATR Inhibitors Berzosertib and Gartisertib Uncovers New Biomarkers and DNA Damage Response Regulators

Rathan Jadav,Florian Weiland,Sylvie M. Noordermeer,Thomas Carroll,Yuandi Gao, Jianming Wang,Houjiang Zhou,Frederic Lamoliatte,Rachel Toth,Thomas Macartney,Fiona Brown,C. James Hastie,Constance Alabert,Haico van Attikum,Frank Zenke,Jean-Yves Masson,John Rouse

MOLECULAR & CELLULAR PROTEOMICSno. 8 (2024)

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ATR Phosphoproteomics - DHX9 Validation

Rathan S Jadav,Florian Weiland,Thomas Carroll,Yuandi Gao, Jianming Wang,Houjiang Zhou,Frédéric Lamoliatte,Iván Muñoz,Rachel Toth,Thomas Macartney,Haico van Attikum,Fiona Brown,James Hastie,Constance Alabert,Frank T. Zenke,Sylvie M. Noordermeer,John Rouse

Zenodo (CERN European Organization for Nuclear Research) (2023)

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Genetic Screening Identifies Integrated Stress Response Kinase HRI (EIF2AK1) As a Negative Regulator of PINK1 and Mitophagy Signalling

Pawan Kishor Singh,Ilaria Volpi,Shalini Agarwal,Léa P. Wilhelm,Giada Becchi,Thomas Macartney,Rachel Toth,Adrien Rousseau,Glenn R. Masson,Ian G. Ganley,Miratul M. K. Muqit

bioRxiv (2023)

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Regulation of Human PINK1 Ubiquitin Kinase by Serine167, Serine228 and Cysteine412 Phosphorylation

Andrew D. Waddell,Hina Ojha,Shalini Agarwal, Christopher J. Clarke,Ana Terriente-Felix,Houjiang Zhou,Poonam Kakade,Axel Knebel, Andrew M. Shaw,Robert Gourlay,Joby Varghese,Renata F. Soares,Rachel Toth,Thomas Macartney,Patrick A. Eyers,Nick Morrice,Richard Bayliss,Alexander J. Whitworth,Claire E. Eyers,Miratul M. K. Muqit

Zenodo (CERN European Organization for Nuclear Research) (2023)

引用3浏览0引用

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