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The lab of molecular cytogenetics at the Institut für Humangenetik in Jena has different research lines, all of them connected by the interest in chromosome structure and evolution. The main research interest is within the frame of clinical genetic research, i.e. the characterization of acquired and inherited chromosomal aberrations with the aim to understand the biological background of how and why such alterations from the normal happen. There are ongoing projects on small supernumerary marker chromosomes , chromosomal heteromorphisms on chromosomes 2 and 9 and fragile sites. In leukemia-research the lab is involved in the search for cryptic, disease-associated or -causing chromosomal aberrations. Besides we are interested in chromosomal evolution and have cowork with other groups working on fish-species (Brasil), turtle (Italy), or Rhodentia (Russia). Apart from multicolor fluorescence in situ hybridization approaches like immunohistochemistry, microsatellite analysis or array-CGH are applied in the research.
研究兴趣
论文共 1036 篇作者统计合作学者相似作者
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Human Ring Chromosomespp.363-399, (2024)
Human Ring Chromosomespp.31-42, (2024)
Human Ring Chromosomespp.3-15, (2024)
Fatima Ouboukss, Zhour El Amrani, Hicham Bouchahta,Ilham Ratbi,Aziza Sbiti,Thomas Liehr,Abdelaziz Sefiani,Abdelhafid Natiq
FRONTIERS IN GENETICS (2024): 1331676-1331676
BMC Biologyno. 1 (2024): 1-16
Nurul Aida Ariffen,Antonio Augusto Ornellas,Gilda Alves, Ahmad Moay Shana'ah, Samiha Sharma,Stefanie Kankel,Elena Jamali, Bernhard Theis,Thomas Liehr
Pathology - Research and Practicepp.155269, (2024)
Christina Keramida,Ioannis Papoulidis, Efterpi Pappa,Thomas Liehr, Konstantinos Kalmantis,Angeliki Gerede,Efterpi Pavlidou,Michael Bjorn Petersen,Emmanouil Manolakos
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