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Thomas Barker explores and therapeutically exploits the fundamental links between fibroblast adaptation to their physical and biochemical microenvironment and their myofibroblastic differentiation during tissue repair, fibrosis and cancer. Dr. Barker is a Professor in Biomedical Engineering in the Schools of Engineering and Medicine at the University of Virginia. He performed his academic and scientific training with Drs. James Hagood, Joanne Murhpy-Ullrich, Helene Sage, and Jeffrey Hubbell prior to his first faculty post at Georgia Institute of Technology, where he spend 10 years as an Assistant and Associate Professor. Dr. Barker’s research integrates engineering and quantitative approaches with basic cell and molecular biology to understand and control cell phenotype through their interactions with natural and engineered extracellular matrices. Dr. Barker is also focused on understanding the fundamental roles of cell mechanotransduction and mechanical forces in regulating the biochemical activity of proteins in the extracellular matrix toward wound repair, regeneration, and fibrosis.
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论文共 147 篇作者统计合作学者相似作者
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Kimberly Nellenbach,Emily Mihalko,Seema Nandi,Drew W Koch,Jagathpala Shetty,Leandro Moretti,Jennifer Sollinger,Nina Moiseiwitsch, Ana Sheridan, Sanika Pandit,Maureane Hoffman,Lauren V Schnabel,
FRONTIERS IN IMMUNOLOGY (2024): 1308594-1308594
Julie Leonard-Duke, Samuel M. J. Agro, David J. Csordas, Anthony C. Bruce, Taylor G. Eggertsen, Tara N. Tavakol,Thomas H. Barker, Catherine A. Bonham, Jeffery J. Saucerman, Lakeshia J. Taite,Shayn M. Peirce
biorxiv(2024)
MATRIX BIOLOGY (2023): 179-193
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