基本信息
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职业迁徙
个人简介
Tesfaye B. Mersha, PhD, is a quantitative geneticist. His background includes an early exposure to the many facets of biology and statistics and interested in cross-line disciplines to understand and solve complex genetic problems. During his post-doctoral fellowship program in statistical and human genetics, Dr. Mersha worked on statistical genetics methodologies and applied genetical data analysis to localize disease genes. Particularly, he focused on genetic analyses of metabolic and mental disorders using linkage, association and admixture mapping approach.
He developed genome-wide ancestry informative markers (AIMs) panel by mining databases including HapMap, Affymetrix and Illumina. The AIM markers are useful in ancestry inference, admixture mapping and structured association testing. He used over 4 million HapMap SNP data and developed approaches of chromosomal based finer population genetic structure characterization, localization of private SNPs and associated genes and pathways that could have pharmacogenomics implication.
In addition, Dr. Mersha is working on gene regulatory networks, gene ontology enrichment analysis and molecular profiling using various biologic and bioinformatic methodology for prioritizing asthma candidate genes. Dr. Mersha’s overall research interest and goal includes the use of population genomics, quantitative genetics, statistical genetics as well as proteomics and biological profiling and pathway methods to understand and dissect common complex diseases.
研究兴趣
论文共 140 篇作者统计合作学者相似作者
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Desalew Salew Tewabe,Muluken Azage,Gizachew Yismaw Wubetu, Sisay Awoke Fenta,Mulugeta Dile Worke, Amanu Mekonen Asres,Wallelign Alemnew Getnet,Genet Gedamu Kassie,Yonatan Menber,Alemtsehay Mekonnen Munea,Taye Zeru, Selamawit Alemayehu Bekele,
The Journal of Allergy and Clinical Immunology: In Practice (2024)
European journal of human genetics : EJHGno. 2 (2024): 139-142
Journal of Allergy and Clinical Immunologyno. 2 (2024): AB251
Journal of Translational Medicineno. 1 (2024): 1-10
Journal of Allergy and Clinical Immunology: Globalno. 2 (2024): 100209-100209
Briefings in bioinformaticsno. 4 (2024)
NUTRIENTSno. 4 (2024): 567
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作者统计
#Papers: 137
#Citation: 2483
H-Index: 25
G-Index: 47
Sociability: 6
Diversity: 0
Activity: 3
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