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Dear chairman and committee members
I am writing here in response to the position of Research Scientist/Sr. Executive in your prestigious research organisation. I, Dr. Tejeswara Rao Allaka, completed my doctoral studies in 2020 at the Centre for Chemical Sciences and Technology, Institute of Science and Technology, Jawaharlal Nehru Technological University Hyderabad, India, Research interests include the synthesis of naturally occurring substances, synthetic organic chemistry, molecular structure characterization, process and preparation of impurities, and computational modeling techniques. Currently, I am looking for a new R & D position and I would like to continue my career at your research organisation.
Presently, I am working as a Sr. Executive in API-R & D at Apothecon Pharmaceuticals Pvt Ltd, Shameerpet, Hyderabad for the year (October 2022-conti…) in the area of API (Rimegepant sulphate and its intermediates) [Main branch-Gujarat]. I have worked as a Senior Supervisor/Sr. Executive in API-R & D at SYMED Labs, Hyderabad for 1 year in the area of APIs (Silnafil, Brivaracetam ect.,) and drug intermediates by route scouting & validation (2021-2022). I have worked as a Research Scientist / Executive in different projects on synthesis of APIs (Lacosamide, Pantoprazole ect.,) and various type of heterocyclic compounds as a part Drug Discovery programme following literature survey and modifying synthetic routes in Metrochem API PVT LTD., Hyderabad, India for 2 years (2019-2021). I have worked as R & D - chemist for the preparation of chemical impurities at GVK Bio Pvt Ltd., Hyderabad (2011). I have worked as Assistant Professor (C) (2011-2013) for master of chemical science students at CCST, IST, JNTUH University, Hyderabad, in the subject areas of Organic Chemistry, Spectroscopy and Spectrometry (1H NMR, 13C NMR, IR, UV, Mass and SEM, TEM analysis), Material Chemistry (Inorganic Chemistry), Retro synthesis, and Chemical laboratories. I have organized and a committee member in several international, national conferences and seminars, as well as refresher courses.
My thesis title “Synthesis and characterization of novel fluoroquinolone molecules and evaluation of their biological activites”. During my PhD, I worked on fluoroquinolone scaffolds and good experience in which are involved fluoroquinolones containing asymmetric citrate conjugates linked to 1,2,4–triazoles, 4–thiazolidinones, 1,3,4–oxadiazoles, 1,2,3–triazoles, 1,3,4–thiadiazines, 1,3,4-thiadiazoles, pyrazoles, pyrroles, tetrazolyl-pyrrolidines via conventional as well as sonochemical techniques. I have been worked on chalcones, quinolone, quinazoline, indole, etodolac, purine nucleosides bridged with different heterocyclic derivatives. All the Final derivatives were done for their spectral analysis like 1H NMR, 13C NMR, IR, UV, Mass and SEM, TEM analysis. All the molecules were done for molecular docking with the active site of DNA gyrase (2XCT, 2XCS, 3FOE, 2ZCS) and Topoisomerase-IV (3IVX, 4KPE), Topoisomerase-IIa (1ZXM), antifungal (5TZ1), KRAS Q61H mutant (6MNX), dehydrogenase type 1 (3HB4), Human PFKFB3 (6IBZ) by Schrödinger, autodock4.2, Gold, Glide protocols and predict their ADMET properties using the SwissADME, ADMETlab2, Molinspiration, Molsoft and Osiris toolkits. During my research tenure I have guided 8 M.Sc., Chemical Science students and after completed my PhD I have guided 3 PhD chemistry students and all of them produced high quality projects and articles. During my PhD study, I published over 30 research articles in international and national journals, 1 Indian patent, 1 De Gruyter book chapter, 1 Elsevier book chapter, and attended more than 22 International and National conferences and presented scientific papers.
With my overall Research and Industrial experience, I am confident that I can be a good part of your research organization. I have attached my Curriculum Vitae, Covering letter for your perusal. I believe my enthusiasm, curiosity, and determination along with my scientific background parallels my research interest in your group. I would be grateful if you could consider my application for the position of Research Scientist Sr. Executive – API process R & D at your organization. Will you require any further clarification of this letter or need any additional information, please do not hesitate to contact me.
I am looking forward for your positive response.
Thanking you
Sincerely,
Dr. Tejeswara Rao Allaka, PhD
Research Scientist, API – R & D
https://orcid.org/0000-0002-3094-2395
https://scholar.google.com/citations?user=mT_-c3IAAAAJ&hl=en
https://www.researchgate.net/profile/Tejeswara-Allaka
https://www.facebook.com/tejeswararao.allaka
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Sudhakar Reddy Baddam, Mahesh Kumar Avula, Raghunadh Akula,Venkateswara Rao Battula, Sudhakar Kalagara, Ravinder Buchikonda, Srinivas Ganta,Srinivasadesikan Venkatesan,Tejeswara Rao Allaka
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Results in Chemistry (2024): 101279
Veera Sankara Pavan Kumar Gudapati, Durga Venkata Phani Kumar Gudapati,Tejeswara Rao Allaka,Naresh Kumar Katari, Mutyalanaidu Ganivada, Sudhakar Reddy Baddam,Sunder Kumar Kolli
RESULTS IN CHEMISTRY (2024)
Kumaraswamy Sadineni, Sravanthi Reddy Basireddy,Tejeswara Rao Allaka, Satyanarayana Yatam, Srinu Bhoomandla, Venkatanaryana Muvvala, Sharath Babu Haridasyam
CHEMISTRY & BIODIVERSITYno. 5 (2024): e202400389-e202400389
Molecular diversitypp.1-17, (2023)
A. K. Dunga,T. Rao Allaka, A. Shaik, R. Νemuri, A. K. Thandlam, S. K. Nechipadappu, P. Pothana,P. V. Ν. N. Kishore
RUSSIAN JOURNAL OF GENERAL CHEMISTRYno. 4 (2023): 949-961
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JOURNAL OF HETEROCYCLIC CHEMISTRYno. 10 (2023): 1666-1683
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