Tak Mak - Department of Medical Biophysics, Temerty Faculty of Medicine, University of Toronto;Department of Pathology, School of Clinical Medicine, University of Hong Kong

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Bio

Our research is concentrated on gaining fundamental knowledge of the biology of cells in normal and disease settings. We have chosen to focus on the mechanisms underlying immune responses and tumorigenesis. With this broad agenda in mind, we have initiated several complementary programs. Many of these projects have evolved from the production and analysis of genetically engineered mouse strains.

Research Interests

Papers共 860 篇Author StatisticsCo-AuthorSimilar Experts

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Lymph Node Macrophages Drive Immune Tolerance and Resistance to Cancer Therapy by Induction of the Immune-Regulatory Cytokine IL-33

Sara Lamorte,Rene Quevedo, Robbie Jin,Luke Neufeld, Zhe Qi Liu, M Teresa Ciudad, Sabelo Lukhele, Jessica Bruce, Shreya Mishra, Xin Zhang,Zaid Kamil Saeed, Hal Berman,Dana J Philpott,Stephen E Girardin,Shane Harding,David H Munn,Tak W Mak, Mikael C I Karlsson,David G Brooks,Tracy L McGaha

Cancer cellno. 5 (2025): 955-969.e10

Cited0Views0WOSBibtex

Supplementary Figure S6 from Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma

Horace H.Y. Lee,Kin Long Chow,Ho Shing Wong,Tsz Yan Chong,Alice S.T. Wong,Grace H.W. Cheng,Jasmine M.K. Ko,Hoi Cheong Siu,Maximus C.F. Yeung,Michael S.Y. Huen,Ka Yu Tse,Mark R. Bray,Tak Wah Mak,Suet Yi Leung,Philip P.C. Ip

crossref（2024）

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HPKI Inhibition and Venetoclax Combination Suppressed AML by Enhancing Cytotoxic T-Cell Response to Leukaemia

Xiaoyuan Zeng, Kwui-Wa Tong,Koon Chuen Chan,Li-Chuan Zheng,Stephen Lam, Mark Robert Bray,Tak-Wah Mak,Cheuk-Him Man,Anskar Y. H. Leung

BLOOD (2024): 2763-2763

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Supplementary Figure S3 from Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma

crossref（2024）

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Supplementary Data S1 from Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma

crossref（2024）

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Supplementary Figure S5 from Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma

crossref（2024）

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Mutant IDH Inhibitors Induce Lineage Differentiation in IDH-mutant Oligodendroglioma

Avishay Spitzer,Simon Gritsch,Masashi Nomura, Alexander Jucht,Jerome Fortin,Ramya Raviram,Hannah R. Weisman,L. Nicolas Gonzalez Castro, Nicholas Druck,Rony Chanoch-Myers,John J. Y. Lee,Ravindra Mylvaganam, Rachel Lee Servis, Jeremy Man Fung,Christine K. Lee,Hiroaki Nagashima,Julie J. Miller,Isabel Arrillaga-Romany,David N. Louis,Hiroaki Wakimoto, Will Pisano,Patrick Y. Wen,Tak W. Mak,Marc Sanson,Mehdi Touat,Dan A. Landau,Keith L. Ligon,Daniel P. Cahill,Mario L. Suva,Itay Tirosh

NEURO-ONCOLOGY（2024）

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Supplementary Table S1 from Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma

crossref（2024）

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IDENTIFICATION OF MODULATORS OF IDH INHIBITOR SENSITIVITY INIDH-MUTATED DIFFUSE GLIOMAS

Sumaiyah Saleek,Eric Laugesen, Poorani Ganesh Subramani,Ruxiao Tian,Annette Wu,Samah El Ghamrasni,Adrian Levine,Zoya Aamir,Kevin Petrecca,Samuel Mcbrayer,Mario Suva,Cynthia Hawkins,Uri Tabori,Tak Mak,Jerome Fortin

NEURO-ONCOLOGY (2024)

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Tak Mak(麦德华)

Professor

Papers共 860 篇Author StatisticsCo-AuthorSimilar Experts