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个人简介
The research of our laboratory is at the interface between virology and proteomics. We are studying cellular mechanisms used in defense against viruses, as well as mechanisms used by viruses to inhibit or hijack host cell processes. For these studies, we use multidisciplinary approaches, integrating molecular virology, cell culture, microscopy, and bioinformatics. We have developed a series of proteomics-based approaches for characterizing cellular processes occurring during the progression of viral infections, and we are exploring several areas of interest:
• Dynamic regulation of host-virus protein-protein and protein-nucleic acid interactions during the progression of an infection
• Mechanisms of sensing of pathogenic DNA within the nuclei of infected cells
• Initiation and propagation of intrinsic and innate immune responses following infection with nuclear-replicating enteroviruses.
• Roles PVSRIPO in the treatment against solid tumor like Prostate cancer.
• Global remodeling of cellular organelles during the progression of viral infection
• Developing and identifying the host pathogen signaling protein in tumor imcro environment, interactions, determining the specificity of interactions, defining distinct protein complexes, and measuring the relative stability of interactions
研究兴趣
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Sohail Zafar Gill,Muhammad Bilal Khan Niazi,Umer Shahzad Malik,Zaib Jahan, Saadia Andleep,Tahir Ahmed
MATERIALS CHEMISTRY AND PHYSICS (2024): 129170
BUSINESS & INFORMATION SYSTEMS ENGINEERINGno. 1 (2024): 67-84
THE 7TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: The 15th Asian Congress on Biotechnology in conjunction with the 7th International Symposium on Biomedical Engineering (ACB-ISBE 2022) AIP Conference Proceedings (2024)
Kousain Kousar, Shaheer Shafiq, Syeda Tahira Sherazi,Fareeha Iqbal,Usman Shareef,Salik Kakar,Tahir Ahmad
Scientific Reportsno. 1 (2024): 1-15
Journal of medical virologyno. 7 (2024): e29748-e29748
FRONTIERS IN IMMUNOLOGY (2024)
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESno. Pt 1 (2024): 128831-128831
Sadia Anjum, Hamile Ali,Faiza Naseer,Maisa S. Abduh, Halima Qadir,Salik Kakar,Yasir Waheed,Tahir Ahmad
Frontiers in immunology (2024): 1391710-1391710
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