Thaddeus A. Tomaszek - Screening and Compound Profiling, GlaxoSmithKline

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论文共 19 篇作者统计合作学者相似作者

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A Highly Potent Inhibitor of Cathepsin K (relacatib) Reduces Biomarkers of Bone Resorption Both in Vitro and in an Acute Model of Elevated Bone Turnover in Vivo in Monkeys

S. Kumar,L. Dare,J. A. Vasko-Moser,I. E. James,S. M. Blake,D. J. Rickard,S. -M. Hwang,T. Tomaszek,D. S. Yamashita,R. W. Marquis, H. Oh,J. U. Jeong,D. F. Veber,M. Gowen,M. W. Lark,G. Stroup

Bone（2007）

引用139浏览0WOSEI引用

139

Structure Activity Relationships of 5-, 6-, and 7-Methyl -Substituted Azepan-3-One Cathepsin K Inhibitors

DS Yamashita,RW Marquis,R Xie, SD Nidamarthy,HJ Oh,JU Jeong,KF Erhard,KW Ward,TJ Roethke,BR Smith,HY Cheng,XL Geng, F Lin,PH Offen, B Wang,N Nevins,MS Head,RC Haltiwanger, AAN Sarjeant,LM Liable-Sands,BG Zhao,WW Smith,CA Janson, E Gao,T Tomaszek,M McQueney, IE Jarnes,CJ Gress,DL Zembryki,MW Lark,DF Veber

Journal of medicinal chemistry（2006）

引用75浏览0WOS引用

Human Methionine Aminopeptidase Complex with 4-Aryl-1,2,3-triazole Inhibitor

L.S. Kallander, Q. Lu, W. Chen,T. Tomaszek,G. Yang,D. Tew,T.D. Meek,G.A. Hofmann, C.K. Schulz-Pritchard,W.W. Smith,C.A. Janson,M.D. Ryan,G.F. Zhang,K.O. Johanson,R.B. Kirkpatrick, T.F. Ho,P.W. Fisher,M.R. Mattern,R.K. Johnson,M.J. Hansbury,J.D. Winkler,K.W. Ward,D.F. Veber,S.K. Thompson

openalex（2005）

引用0浏览0引用

Azepanone-based Inhibitors of Human Cathepsin L

RW Marquis,I James,J Zeng, REL Trout,S Thompson,A Rahman,DS Yamashita,R Xie,Y Ru,CJ Gress,S Blake, MA Lark,SM Hwang,T Tomaszek, P Offen,MS Head,MD Cummings,DF Veber

Journal of Medicinal Chemistry（2005）

引用27浏览0WOS引用

A highly potent inhibitor of cathepsin K inhibits bone resorption both in vitro and in acute model of bone resorption in vivo in monkeys

S Kumar,L Dare,JA Vasko-Moser,SM Hwang,T Tomaszek,DS Yamashita,RW Marquis, H Oh,JU Jeong,DF Veber,M Gowen,G Stroup

JOURNAL OF BONE AND MINERAL RESEARCH（2005）

引用0浏览0引用

Efficient Production And Activation Of Cathepsins By Expressing As Fc Fusion Proteins In Cho Secretion System

R Matico, D Chalupowicz, M Burns,G Scott,T Tomaszek, C Hissong,M Mcqueney,J Trill,K Johanson

FASEB JOURNAL（2004）

引用0浏览0引用

Sars 3clpro; Efficient Expression And Purification For Assay Development And Crystallography

J Martin,Hz Zhao,S Sweitzer, T Lewis,J Kerrigan,G Scott,T Tomaszek,M Mcqueney,A Hassell,L Shewchuk,K Johanson

FASEB JOURNAL（2004）

引用0浏览0引用

Potent inhibition of cathepsin K results in inhibition of bone resorption in vitro and in vivo in non-human primates

GB Stroup,MW Lark,DF Veber,SM Blake,LC Dare, LA Day,KF Erhard,SM Hwang,IE James,JU Jeong,SJ Hoffman,RW Marquis,M Mcqueney,HJ Oh, CR Person,JA Vasko-Moser,T Tomaszek,DS Yamashita, S Kumar

JOURNAL OF BONE AND MINERAL RESEARCH（2003）

引用0浏览0引用

Novel Inhibitors of the Osteoclast Specific Cysteine Protease, Cathepsin K

DF Veber,DS Yamashita,HJ Oh,BR Smith,K Salyers,M Levy,CP Lee,A Marzulli,P Smith,T Tomaszek,D Tew,M McQueney,GB Stroup,MW Lark,IE James

Peptides for the New Millennium American Peptide Symposiapp.453-455

引用3浏览0引用

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