基本信息
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Bio
Dr. Komarova’s research program is aimed at understanding the regulation of osteoclasts, the cells responsible for bone destruction in diseases such as osteoporosis, rheumatoid arthritis, periodontitis and bone metastases. Osteoclasts are highly active cells, present in bone only in small numbers. Moreover, osteoclasts are terminally differentiated, and therefore do not proliferate in culture. To understand the mechanisms that determine stimulus-specific gene expression in osteoclasts, Dr. Komarova’s laboratory employs high-speed imaging of live cells, quantitative gene expression analysis, as well as mathematical modeling. These studies will provide new insights into the control of bone resorption in health and disease, which may lead to the development of new therapies for treatment of inflammatory, metabolic and metastatic bone disorders.
Research Interests
Papers共 136 篇Author StatisticsCo-AuthorSimilar Experts
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JOURNAL OF PAINno. 2 (2024): 545-556
Madalina Patron, Mattias Neset, Mariia Mielkozorova,Daniel G. Bisson,Marie Vigouroux,Juan Pablo Cata,Pablo M. Ingelmo,Jean A. Ouellet,Lisbet Haglund,Svetlana Komarova
JOURNAL OF PAIN RESEARCH (2024): 1683-1692
Elizabeth A. Zimmermann, Taylor DeVet,Myriam Cilla,Laia Albiol,Kyle Kavaseri, Christine Andrea,Catherine Julien,Kerstin Tiedemann,Arash Panahifar,Sima Alidokht,Richard Chromik,Svetlana V. Komarova,
Matrix Biology Plus (2024): 100155
PLOS ONEno. 1 (2024)
L. van Haasterecht,C. Dsouza, Y. Ma,H. I. Korkmaz, Y. de Jong,J. C. F. Ket,P. P. M. van Zuijlen,M. L. Groot,S. V. Komarova
FRONTIERS IN MECHANICAL ENGINEERING-SWITZERLAND (2023)
JOURNAL OF BONE AND MINERAL RESEARCH (2023): 201-202
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REVIEWS IN ENDOCRINE & METABOLIC DISORDERSno. 6 (2023): 1103-1119
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Author Statistics
#Papers: 131
#Citation: 3555
H-Index: 34
G-Index: 56
Sociability: 6
Diversity: 3
Activity: 31
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