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Bio
The Cloonan lab focuses on understanding how cellular iron metabolism is regulated in the lung and how dysregulation of iron uptake, release or turnover contributes to disease processes.
We also seek to understand how iron and the mitochondrion interact. Mitochondria are the primary storage sites for iron inside the cell, yet how iron is transported in and out of the mitochondrion and how iron regulates mitochondrial homeostasis remains to be fully determined.
We primarily focus on the discovery of novel diagnostic and/or therapeutic approaches to treat chronic lung diseases focusing on Chronic Obstructive Pulmonary Disease (COPD) and Idiopathic Pulmonary Fibrosis (IPF). However, our research goals have broader implications for other diseases involving iron metabolism and mitochondrial dysfunction.
Research Interests
Papers共 90 篇Author StatisticsCo-AuthorSimilar Experts
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Karosham Diren Reddy,Nikoleta Bizymi, Anja Schweikert, Sachin Ananth,Clarice X Lim,Katharine M Lodge,Audrey Joannes,Niki Ubags,Anne M van der Does,Suzanne M Cloonan,Arnaud Mailleux,Nahal Mansouri,
ERJ open researchno. 2 (2024)
Li-Chao Fan, Keith McConn,Maria Plataki,Sarah Kenny,Niamh C Williams,Kihwan Kim,Jennifer A Quirke, Yan Chen,Maor Sauler,Matthias E Möbius,Kuei-Pin Chung, Estela Area Gomez,
American Journal of Respiratory and Critical Care Medicine (2023)
American journal of respiratory cell and molecular biologyno. 4 (2023): 458-462
American journal of respiratory cell and molecular biologyno. 4 (2022): 347-348
Idiopathic interstitial pneumonias (2022)
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