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In collaboration with Dr. David Cherney, I am currently a site investigator/Co-Investigator at UHN for two clinical trials: 1) DAPA CKD: A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients with Chronic Kidney Disease and 2) A double-blind, placebo controlled, cross-over renal mechanistic trial to assess the effect of adding empagliflozin versus placebo on renal hyperfiltration in patients with type 1 diabetes on a background of the angiotensin converting enzyme inhibitor (ACEi) Ramipril: BETWEEN study. I also have a research interest in Pancreas Transplantation. I am currently a Co-Investigator (PI: Dr. Cherney, Co-I: Dr. Kim, Dr. Cattral) on a pilot study evaluating the impact of pancreas transplantation on the complications of Type 1diabetes (BBDC Sun Life Financial Pilot and Feasibility Grant) and have published clinical outcomes research in patients with type 1 diabetes with pancreatic transplants. I also have interest in understanding the pathogenesis of recurrent diabetic kidney disease (DKD) in the kidney allograft and therapies for DKD in the transplant population. Our group has recently published our experience describing the safety and efficacy of SGLT2 inhibitors in a group of kidney and kidney-pancreas transplant recipients.
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论文共 33 篇作者统计合作学者相似作者
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Journal of the American Society of Nephrologyno. 11S (2023): 1030-1030
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGYno. 4 (2022): 665-673
Vikas S Sridhar, Jaya Prakash N Ambinathan,Pieter Gillard,Chantal Mathieu,David Z I Cherney,Yuliya Lytvyn,Sunita K Singh
Ali Vedadi,Aarushi Bansal, Priscilla Yung,Olusegun Famure, Margot Mitchell,Amy D Waterman,Sunita K Singh,Marta Novak,Sang Joseph Kim,Istvan Mucsi
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