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Suhail Ahmed Kabeer Rasheed is a molecular biologist keen on elucidating the role of complex signaling pathways in tumorigenesis, metastasis and resistance to therapies including immuno-therapy. He is an Assistant Professor in the Programme of Cancer and Stem Cell Biology at Duke-NUS. In addition, he is a trained expert in Team Based Learning and was a co-coordinator of the GMS1000 module. He has recently shown that a specific GTP binding protein (Ga13, encoded by GNA13) is highly expressed in solid tumors including prostate, breast and head and neck cancers and induces treatment resistance by inducing a cancer stem cell like program in these solid tumors. Using various overexpression and knockdown/knockout models of G proteins in cancer cells he is keen on elucidating the mechanisms that mediate the induction of cancer stem cells, drug resistance and immune evasion in variety of solid tumors. He is an expert in genome editing using CRISPR/CAS9, post transcriptional gene regulation through microRNAs and mouse xenograft models to test drug resistance, cancer stem cell and immune evasion phenotypes. Ultimately, Dr. Rasheed aims to understand the mechanisms that drive immune evasion, drug resistance and metastasis in solid tumors and identify novel targets to treat cancers in the future.
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论文共 25 篇作者统计合作学者相似作者
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Suhail Ahmed Kabeer Rasheed,Dipti Thakkar, Shalini Paliwal, Wen Jie Chin, Akshaya Bansal, Ben Ayers, Che Theng Ng, Brendon Hanson,Piers Ingram,Jerome Boyd-Kirkup
CANCER RESEARCHno. 7 (2023)
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Annemarie Schwab,Aarif Siddiqui,Maria Eleni Vazakidou,Francesca Napoli,Martin Böttcher, Bianca Menchicchi,Umar Raza,Özge Saatci, Angela M. Krebs,Fulvia Ferrazzi,Ida Rapa, Katja Dettmer-Wilde,
crossref(2023)
Annemarie Schwab,Aarif Siddiqui,Maria Eleni Vazakidou,Francesca Napoli,Martin Böttcher, Bianca Menchicchi,Umar Raza,Özge Saatci, Angela M. Krebs,Fulvia Ferrazzi,Ida Rapa, Katja Dettmer-Wilde,
crossref(2023)
Annemarie Schwab,Aarif Siddiqui, Maria Eleni Vazakidou,Francesca Napoli,Martin Böttcher, Bianca Menchicchi,Umar Raza,Özge Saatci, Angela M. Krebs,Fulvia Ferrazzi,Ida Rapa, Katja Dettmer-Wilde,
crossref(2023)
Suhail Ahmed Kabeer Rasheed, Lalitha Vaishnavi Subramanyan,Wei Kiang Lim,Udhaya Kumari Udayappan,Mei Wang,Patrick J Casey
Suhail Ahmed Kabeer Rasheed, Lalitha Vaishnavi Subramanyan,Wei Kiang Lim, Udhaya Kumari Udayappan,Mei Wang,Patrick J. Casey
Oncogeneno. 2 (2021): 147-158
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