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Research Interests
The Bensinger laboratory is focused on understanding how lipid metabolism influences the growth, survival and function of rapidly dividing normal and neoplastic cells. His laboratory recently revealed a lipid metabolic checkpoint that regulates cell cycle progression, cellular growth and viability in lymphocytes. Key ongoing studies include elucidating the signal transduction and regulatory networks that link growth receptor signaling to lipid anabolic programs in the adaptive immune system. We are also interested in understanding how lipid signals influence adaptive immune responses and self-tolerance. Current studies in the laboratory have found that dysregulation of lipid metabolism intrinsically influences adaptive immune cell function and autoimmune pathogenesis. Other important studies in the laboratory are focused on determining if lipid metabolic programs contribute to carcinogenesis, tumor growth and pathogenesis. Finally, we continue to seek out how to target key aspects of lipid metabolism to decrease tumor growth and alter immune cell function.
The Bensinger laboratory is focused on understanding how lipid metabolism influences the growth, survival and function of rapidly dividing normal and neoplastic cells. His laboratory recently revealed a lipid metabolic checkpoint that regulates cell cycle progression, cellular growth and viability in lymphocytes. Key ongoing studies include elucidating the signal transduction and regulatory networks that link growth receptor signaling to lipid anabolic programs in the adaptive immune system. We are also interested in understanding how lipid signals influence adaptive immune responses and self-tolerance. Current studies in the laboratory have found that dysregulation of lipid metabolism intrinsically influences adaptive immune cell function and autoimmune pathogenesis. Other important studies in the laboratory are focused on determining if lipid metabolic programs contribute to carcinogenesis, tumor growth and pathogenesis. Finally, we continue to seek out how to target key aspects of lipid metabolism to decrease tumor growth and alter immune cell function.
Research Interests
Papers共 130 篇Author StatisticsCo-AuthorSimilar Experts
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Andréa B Ball,Anthony E Jones, Kaitlyn B Nguyễn, Amy Rios, Nico Marx,Wei Yuan Hsieh,Krista Yang,Brandon R Desousa,Kristen K O Kim,Michaela Veliova, Zena Marie Del Mundo,Orian S Shirihai,
bioRxiv : the preprint server for biology (2024)
bioRxiv the preprint server for biology (2024)
Holly R Steach,Autumn G York,Mathias H Skadow,Shuting Chen,Jun Zhao,Kevin J Williams, Quan Zhou, Weu-Yuan Hsieh,J Richard Brewer,Rihao Qu,Justin A Shyer, Christian Harman,
bioRxiv : the preprint server for biology (2024)
Anthony E Jones, Amy Rios, Neira Ibrahimovic, Carolina Chavez,Nicholas A Bayley,Andréa B Ball,Wei Yuan Hsieh,Alessandro Sammarco, Amber R Bianchi, Angel A Cortez,Thomas G Graeber,Alexander Hoffmann,
bioRxiv : the preprint server for biology (2024)
Natureno. 8004 (2024): 628-635
EMBO reportsno. 10 (2023)
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