基本信息
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Bio
An international leader in the area of nutrition, obesity, metabolism and cancer, his lab focuses on the molecular and metabolic mechanisms underlying obesity-cancer associations, and the impact of obesity- energy balance modulation (eg, calorie restriction and exercise) or pharmacologic agents on cancer development, progression, and responses to chemotherapy. Primarily using genetically engineered mouse models of breast cancer (recently in parallel with several clinical trials), colon cancer and pancreatic cancer, Dr. Hursting has identified the IGF1/Akt/mTOR and NF-kB signaling pathways as key targets for breaking the obesity-cancer link. His publications establish causal links between obesity, cancer and several systemic factors (including IGF-1, insulin, leptin and IL-6) and components of their downstream signaling pathways (including mTOR and NF-kb).
Research Interests
Papers共 529 篇Author StatisticsCo-AuthorSimilar Experts
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Cancer researchno. 6_Supplement (2024): 1790-1790
Elaine M. Glenny,Alyssa N. Ho,Violet A. Kiesel, Fangxin Chen,Claire E. Gates,Evan M. Paules, Ruihan Xu, C. Alex Holt,Michael F. Coleman,Stephen D. Hursting
bioRxiv the preprint server for biology (2024)
Alyssa N. Ho,Violet A. Kiesel,Claire E. Gates, Bennett H. Brosnan, Scott P. Connelly,Elaine M. Glenny,Alyssa J. Cozzo,Stephen D. Hursting,Michael Francis Coleman
Carolina Digital Repository (University of North Carolina at Chapel Hill) (2024)
Elaine M. Glenny,Tengda Lin, Victoria M. Bandera,Biljana Gigic,Aik Choon Tan,Babak Mirminachi, Saratchandra S. Khumukcham, Alessandro Carpanese,Christy A. Warby, Olena Aksonova,Caroline Himbert,Jennifer Ose,
Cancer researchno. 6_Supplement (2024): 2190-2190
CANCER RESEARCHno. 3 (2024)
Elaine M. Glenny,Alyssa N. Ho,Violet A. Kiesel, Fangxin Chen,Claire E. Gates,Evan M. Paules, Ruihan Xu, C. Alex Holt,Michael F. Coleman,Stephen D. Hursting
Cancer researchno. 6_Supplement (2024): 2189-2189
Cancer Researchno. 6_Supplement (2024): 1784-1784
Michael F. Coleman,Eylem Kulkoyluoglu Cotul,Alexander J. Pfeil,Emily N. Devericks,Muhammad H. Safdar,Marvis Monteiro,Hao Chen,Alyssa N. Ho,Numair Attaar, Hannah M. Malian,Violet A. Kiesel, Alexis Ramos,
Breast Cancer Researchno. 1 (2024): 1-20
Yuan-yuan Li,Supradeep S. Madduri,Erika T. Rezeli, Charlene Santos, Herman Freeman III, Jing Peng,Susan L. McRitchie, Wimal Pathmasiri,Stephen D. Hursting,Susan J. Sumner, Delisha A. Stewart
Carolina Digital Repository (University of North Carolina at Chapel Hill) (2024)
Carol Fabian, Adrian Zelenchuk,Kandy Powers,Amy Kreutzjans, Krystal Pittman, Bill Hendry, Christy Altman,Erin Giles,Katherine L. Cook,Stephen Hursting,Bruce Kimler
Cancer Researchno. 9_Supplement (2024): PO2-08
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Author Statistics
#Papers: 535
#Citation: 17847
H-Index: 66
G-Index: 124
Sociability: 7
Diversity: 3
Activity: 349
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