My group uses advanced multimodal MR and PET imaging to understand the heterogeneity of gliomas (high and low grade) in individual patients. We know that gliomas are among the most heterogeneous tumours but still do not have a method of detecting this heterogeneity. My work focuses on two areas: 1 - Intertumoural heterogeneity (i.e. differences between individuals), especially heterogeneity of tumour invasion; 2- Intratumoural heterogeneity (i.e. differences within a tumour in an individual patient). Our work studies variation of response to chemotherapy/radiotherapy and drug uptake.