基本信息
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职业迁徙
个人简介
Research objectives
Study the structure and function of known DDR proteins, and identify important new DDR proteins and determine how these function in mammalian cells.
Explore how DDR events are affected by chromatin structure, cell cycle status and other parameters such as post-translational modifications.
Use new technologies such as gene editing and whole genome sequencing to explore the sensitivities/resistance mechanisms of DDR proteins in response to DNA-damaging agents and DDR inhibitors. This may identify potential therapeutic targets for generating new anti-cancer agents.
研究兴趣
论文共 416 篇作者统计合作学者相似作者
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Christopher J. Carnie,Maximilian J. Gotz, Chloe S. Palma-Chaundler,Pedro Weickert, Amy Wanders,Almudena Serrano-Benitez,Hao-Yi Li,Vipul Gupta,Samah W. Awwad, Christian J. Blum,Matylda Sczaniecka-Clift,Jacqueline Cordes,
EMBO JOURNALno. 12 (2024): 2397-2423
Christopher J. Carnie,Aleida C. Acampora,Aldo S. Bader, Chimeg Erdenebat,Shubo Zhao, Elnatan Bitensky,Diana van den Heuvel,Avital Parnas,Vipul Gupta, Giuseppina DAlessandro,Matylda Sczaniecka-Clift,Pedro Weickert,
NATURE CELL BIOLOGYno. 5 (2024): 1-14
Almudena Serrano-Benitez,Sophie E. Wells, Lylah Drummond-Clarke,Lilian C. Russo,John Christopher Thomas, Giovanna A. Leal,Mark Farrow, James Michael Edgerton,Shankar Balasubramanian,Ming Yang,Christian Frezza,Amit Gautam,
EMBO JOURNALno. 18 (2023): e113190-e113190
Christopher J. Carnie,Maximilian J. Götz, Chloe S. Palma-Chaundler,Pedro Weickert, Amy R. Wanders,Almudena Serrano-Benitez,Hao-Yi Li,Vipul Gupta, Christian J. Blum,Matylda Sczaniecka-Clift,Guido Zagnoli-Vieira, Giuseppina D’Alessandro,
biorxiv(2023)
Cell genomicsno. 8 (2023): 100362-100362
Giuseppina D'Alessandro,David A. Morales-Juarez, Sean L. Richards,Karin C. Nitiss,Almudena Serrano-Benitez, Juanjuan Wang,John C. Thomas,Vipul Gupta,Andrea Voigt,Rimma Belotserkovskaya, Chen Gang Goh,Anne Ramsay Bowden,
biorxiv(2022)
Zhiming Yu,Yue Wang,Fengling Mei, Haiting Yan,Zhenhui Jin, Pengcheng Zhang,Xian Zhang, Mahmut Tör,Stephen Jackson, Nongnong Shi,Yiguo Hong
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