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Bio
Expertise Summary
Molecular Pharmacology of GPCRs
Fluorescence Correlation Spectroscopy (FCS, FCCS, RICS, PCH)
Single cell pharmacology (binding and function)
Live cell confocal microscopy (fluorescent ligand binding, receptor trafficking)
Advanced imaging approaches (FLIM, FRAP)
Single cell calcium measurements
Cell microinjection
Radioligand binding
Second messenger assays (inositol phosphates, cAMP)
Western blotting and immunoprecipitation
I am particularly focussed on G protein-coupled receptors, and the application of advanced microscopy to study their pharmacology at the single and sub-cellular level.
Molecular Pharmacology of GPCRs
Fluorescence Correlation Spectroscopy (FCS, FCCS, RICS, PCH)
Single cell pharmacology (binding and function)
Live cell confocal microscopy (fluorescent ligand binding, receptor trafficking)
Advanced imaging approaches (FLIM, FRAP)
Single cell calcium measurements
Cell microinjection
Radioligand binding
Second messenger assays (inositol phosphates, cAMP)
Western blotting and immunoprecipitation
I am particularly focussed on G protein-coupled receptors, and the application of advanced microscopy to study their pharmacology at the single and sub-cellular level.
Research Interests
Papers共 135 篇Author StatisticsCo-AuthorSimilar Experts
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Biochemical pharmacology (2024): 116396-116396
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2024)
BRITISH JOURNAL OF PHARMACOLOGYno. 4 (2023): 484-485
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Archives of Biochemistry and Biophysics (2023): 109915-109915
BRITISH JOURNAL OF PHARMACOLOGY (2023): 685-686
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Sebastian Dekkers,Dehan Comez, Noemi Karsai, Marta Arimont-Segura,Meritxell Canals,Birgit Caspar,Chris de Graaf,Laura E. Kilpatrick,Rob Leurs,Barrie Kellam,Stephen J. Hill,Stephen J. Briddon,
ACS medicinal chemistry lettersno. 1 (2023): 143-148
Owen Underwood,Sebastian Fritzwanker, Jaqueline Glenn, Arisbel Batista-Gondin,Julia Drube,Carsten Hoffman,Stephen J Briddon, Stefan Schulz,Meritxell Canals
biorxiv(2023)
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