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个人简介
My Ph.D. work at the University of Leeds with John Barr, provided the motivation to study the cellular organisation of mammalian cells and their interactions with viruses during infection. In this work, I examined the structure of negative-sense RNA virus nulceocapsid proteins using X-ray crystallography. At the time, I was inspired by looking into these proteins’ functions by visualizing their high-resolution structure, but I was also fascinated by the bigger picture and intrigued at the thought of visualizing viral replication machines directly and under native conditions. To accomplish this, I joined Grant Jensen’s lab at Caltech, where all the tools were in place to visualize viruses and explore their architecture within cells. I subsequently began developing cryogenic correlated light and electron microscopy (cryo-CLEM)/electron cryo-tomography (cryo-ET) approaches to perform structural studies on viral infection, and more general cell biology orientated events.
研究兴趣
论文共 43 篇作者统计合作学者相似作者
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Eva Martin-Solana,Stephen D Carter,Eric K F Donahue,Jiying Ning,Jill R Glausier,Matias A Preisegger,Leanna Eisenman,Paul N Joseph,Cedric Bouchet-Marquis,Ken Wu, Catherina L Mobini, Amber N Frantz,
bioRxiv : the preprint server for biology (2024)
bioRxiv : the preprint server for biology (2023)
bioRxiv (Cold Spring Harbor Laboratory) (2022)
Microscopy and Microanalysisno. S1 (2021): 2566-2568
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作者统计
#Papers: 44
#Citation: 821
H-Index: 18
G-Index: 28
Sociability: 5
Diversity: 2
Activity: 21
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