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Bio
Dr. Staudt pioneered the use of gene expression profiling to discover molecularly and clinically distinct cancer subtypes and to predict response to therapy. He defined molecular subtypes of lymphoma that were previously unrecognized but are now viewed as distinct diseases that arise from different stages of B-cell differentiation, utilize different oncogenic mechanisms, and offer new therapeutic targets. To develop new treatments for lymphoid malignancies, Dr. Staudt’s laboratory uses various high-throughput approaches, including cancer gene resequencing, RNAi/CRISPR-based genetic screens, and combinatorial small molecule screens. The laboratory also conducts genomic investigations within therapeutic trials of targeted agents in lymphoma to define mechanisms of response and resistance.
Dr. Staudt is currently Co-Chief of the NCI Lymphoid Malignancies Branch and Director of the NCI Center for Cancer Genomics (CCG) which encompasses several projects including GDC. He has received numerous awards for his research, including the 2009 Dameshek Prize from the American Society of Hematology for outstanding contribution in hematology and election to the National Academy of Sciences in 2013.
Dr. Staudt is currently Co-Chief of the NCI Lymphoid Malignancies Branch and Director of the NCI Center for Cancer Genomics (CCG) which encompasses several projects including GDC. He has received numerous awards for his research, including the 2009 Dameshek Prize from the American Society of Hematology for outstanding contribution in hematology and election to the National Academy of Sciences in 2013.
Research Interests
Papers共 733 篇Author StatisticsCo-AuthorSimilar Experts
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The New England journal of medicineno. 23 (2024): 2143-2155
CANCER CELLno. 5 (2024): 833-849.e12
Constanze Schneider, Hermes Spaink, Gabriela Alexe,Neekesh V Dharia, Ashleigh Meyer, Lucy A Merickel,Delan Khalid,Sebastian Scheich,Bjorn Haupl,Louis M Staudt,Thomas Oellerich,Kimberly Stegmaier
Cancer research (2024)
Leukemia (2024)
Jigar V Desai,Marissa A Zarakas, Andrew L Wishart,Mark Roschewski,Mariano A Aufiero,Ágnes Donkó,Gustaf Wigerblad,Neta Shlezinger, Markus Plate,Matthew R James,Jean K Lim,Gulbu Uzel,
The Journal of clinical investigation (2024)
Cancer Researchno. 6_Supplement (2024): 3913-3913
CELL REPORTSno. 4 (2024): 114105-114105
crossref(2024)
Cancer researchno. 9 (2024): 1388-1395
crossref(2024)
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Author Statistics
#Papers: 732
#Citation: 118943
H-Index: 152
G-Index: 342
Sociability: 9
Diversity: 0
Activity: 3
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